YHL009W-B Protein Information

Systematic Name	Yhl009w-bp
Description	Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes (1, 2)

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	1,802
Molecular Weight (Da)	207,968
Isoelectric Point (pI)	8.46

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Yhl009w-bp (InterPro)
Physical Interactions	There are 5 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000016833E \| P0C2J7 NCBI: 134034968 \| 7839180 \| NP_058133.1 \| NM_001184404.1 GenBank/EMBL/DDBJ: DAA06678.1 \| U11581
External Classifications	EC: 2.7.7.49 [RNA-directed DNA polymerase] EC: 2.7.7.7 [DNA-directed DNA polymerase] EC: 3.1.26.4 [Ribonuclease H] EC: 3.4.23.- [Aspartic Endopeptidases]

Amino Acid Sequence (or in FASTA format)
1 MATPVRDETR NVIDDNISAR IQSKVKTNDT VRQTPSSLRK VSIKDEQVKQ 51 YQRNLNRFKT ILNGLKAEEE KLSETDDIQM LAEKLLKLGE TIDKVENRIV 101 DLVEKIQLLE TNENNNILHE HIDATGTYYL FDTLTSTNKR FYPKDCVFDY 151 RTNNVENIPI LLNNFKKFIK KYQFDDVFEN DIIEIDPREN EILCKIIKEG 201 LGESLDIMNT NTTDIFRIID GLKNKYRSLH GRDVRIRAWE KVLVDTTCRN 251 SALLMNKLQK LVLMEKWIFS KCCQDCPNLK DYLQEAIMGT LHESLRNSVK 301 QRLYNIPHNV GINHEEFLIN TVIETVIDLS PIADDQIENS CMYCKSVFHC 351 SINCKKKPNR ELGLTRPISQ KPIIYKVHRD NNNLSPVQNE QKSWNKTQKK 401 SNKVYNSKKL VIIDTGSGVN ITNDKTLLHN YEDSNRSTRF FGIGKNSSVS 451 VKGYGYIKIK NGHNNTDNKC LLTYYVPEEE STIISCYDLA KKTKMVLSRK 501 YTRLGNKIIK IKTKIVNGVI HVKMNELIER PSDDSKINAI KPTSSPGFKL 551 NKRSITLEDA HKRMGHTGIQ QIENSIKHNH YEESLDLIKE PNEFWCQTCK 601 ISKATKRNHY TGSMNNHSTD HEPGSSWCMD IFGPVSSSNA DTKRYMLIMV 651 DNNTRYCMTS THFNKNAETI LAQIRKNIQY VETQFDRKVR EINSDRGTEF 701 TNDQIEEYFI SKGIHHILTS TQDHAANGRA ERYIRTIVTD ATTLLRQSNL 751 RVKFWEYAVT SATNIRNCLE HKSTGKLPLK AISRQPVTVR LMSFLPFGEK 801 GIIWNHNHKK LKPSGLPSII LCKDPNSYGY KFFIPSKNKI VTSDNYTIPN 851 YTMDGRVRNT QNIYKSHQFS SHNDNEEDQI ETVTNLCEAL ENYEDDNKPI 901 TRLEDLFTEE ELSQIDSNAK YPSPSNNLEG DLDYVFSDVE ESGDYDVESE 951 LSTTNTSIST DKNKILSNKD FNSELASTEI SISEIDKKGL INTSHIDEDK 1001 YDEKVHRIPS IIQEKLVGSK NTIKINDENR ISDRIRSKNI GSILNTGLSR 1051 CVDITDESIT NKDESMHNAK PELIQEQFNK TNHETSFPKE GSIGTNVKFR 1101 NTDNEISLKT GDTSLPIKTL ESINNHHSND YSTNKVEKFE KENHHPPPIE 1151 DIVDMSDQTD MESNCQDGNN LKELKVTDKN VPTDNGTNVS PRLEQNIEAS 1201 GSPVQTVNKS AFLNKEFSSL NMKRKRKRHD KNNSLTSYEL ERDKKRSKRN 1251 RVKLIPDNME TVSAQKIRAI YYNEAISKNP DLKEKHEYKQ AYHKELQNLK 1301 DMKVFDVDVK YSRSEIPDNL IVPTNTIFTK KRNGIYKARI VCRGDTQSPD 1351 TYSVITTESL NHNHIKIFLM IANNRNMFMK TLDINHAFLY AKLEEEIYIP 1401 HPHDRRCVVK LNKALYGLKQ SPKEWNDHLR QYLNGIGLKD NSYTPGLYQT 1451 EDKNLMIAVY VDDCVIAASN EQRLDEFINK LKSNFELKIT GTLIDDVLDT 1501 DILGMDLVYN KRLGTIDLTL KSFINRMDKK YNEELKKIRK SSIPHMSTYK 1551 IDPKKDVLQM SEEEFRQGVL KLQQLLGELN YVRHKCRYDI NFAVKKVARL 1601 VNYPHERVFY MIYKIIQYLV RYKDIGIHYD RDCNKDKKVI AITDASVGSE 1651 YDAQSRIGVI LWYGMNIFNV YSNKSTNRCV SSTEAELHAI YEGYADSETL 1701 KVTLKELGEG DNNDIVMITD SKPAIQGLNR SYQQPKEKFT WIKTEIIKEK 1751 IKEKSIKLLK ITGKGNIADL LTKPVSASDF KRFIQVLKNK ITSQDILAST 1801 DY*

Amino Acid Sequence (or in FASTA format)

       1  MATPVRDETR NVIDDNISAR IQSKVKTNDT VRQTPSSLRK VSIKDEQVKQ
      51  YQRNLNRFKT ILNGLKAEEE KLSETDDIQM LAEKLLKLGE TIDKVENRIV
     101  DLVEKIQLLE TNENNNILHE HIDATGTYYL FDTLTSTNKR FYPKDCVFDY
     151  RTNNVENIPI LLNNFKKFIK KYQFDDVFEN DIIEIDPREN EILCKIIKEG
     201  LGESLDIMNT NTTDIFRIID GLKNKYRSLH GRDVRIRAWE KVLVDTTCRN
     251  SALLMNKLQK LVLMEKWIFS KCCQDCPNLK DYLQEAIMGT LHESLRNSVK
     301  QRLYNIPHNV GINHEEFLIN TVIETVIDLS PIADDQIENS CMYCKSVFHC
     351  SINCKKKPNR ELGLTRPISQ KPIIYKVHRD NNNLSPVQNE QKSWNKTQKK
     401  SNKVYNSKKL VIIDTGSGVN ITNDKTLLHN YEDSNRSTRF FGIGKNSSVS
     451  VKGYGYIKIK NGHNNTDNKC LLTYYVPEEE STIISCYDLA KKTKMVLSRK
     501  YTRLGNKIIK IKTKIVNGVI HVKMNELIER PSDDSKINAI KPTSSPGFKL
     551  NKRSITLEDA HKRMGHTGIQ QIENSIKHNH YEESLDLIKE PNEFWCQTCK
     601  ISKATKRNHY TGSMNNHSTD HEPGSSWCMD IFGPVSSSNA DTKRYMLIMV
     651  DNNTRYCMTS THFNKNAETI LAQIRKNIQY VETQFDRKVR EINSDRGTEF
     701  TNDQIEEYFI SKGIHHILTS TQDHAANGRA ERYIRTIVTD ATTLLRQSNL
     751  RVKFWEYAVT SATNIRNCLE HKSTGKLPLK AISRQPVTVR LMSFLPFGEK
     801  GIIWNHNHKK LKPSGLPSII LCKDPNSYGY KFFIPSKNKI VTSDNYTIPN
     851  YTMDGRVRNT QNIYKSHQFS SHNDNEEDQI ETVTNLCEAL ENYEDDNKPI
     901  TRLEDLFTEE ELSQIDSNAK YPSPSNNLEG DLDYVFSDVE ESGDYDVESE
     951  LSTTNTSIST DKNKILSNKD FNSELASTEI SISEIDKKGL INTSHIDEDK
    1001  YDEKVHRIPS IIQEKLVGSK NTIKINDENR ISDRIRSKNI GSILNTGLSR
    1051  CVDITDESIT NKDESMHNAK PELIQEQFNK TNHETSFPKE GSIGTNVKFR
    1101  NTDNEISLKT GDTSLPIKTL ESINNHHSND YSTNKVEKFE KENHHPPPIE
    1151  DIVDMSDQTD MESNCQDGNN LKELKVTDKN VPTDNGTNVS PRLEQNIEAS
    1201  GSPVQTVNKS AFLNKEFSSL NMKRKRKRHD KNNSLTSYEL ERDKKRSKRN
    1251  RVKLIPDNME TVSAQKIRAI YYNEAISKNP DLKEKHEYKQ AYHKELQNLK
    1301  DMKVFDVDVK YSRSEIPDNL IVPTNTIFTK KRNGIYKARI VCRGDTQSPD
    1351  TYSVITTESL NHNHIKIFLM IANNRNMFMK TLDINHAFLY AKLEEEIYIP
    1401  HPHDRRCVVK LNKALYGLKQ SPKEWNDHLR QYLNGIGLKD NSYTPGLYQT
    1451  EDKNLMIAVY VDDCVIAASN EQRLDEFINK LKSNFELKIT GTLIDDVLDT
    1501  DILGMDLVYN KRLGTIDLTL KSFINRMDKK YNEELKKIRK SSIPHMSTYK
    1551  IDPKKDVLQM SEEEFRQGVL KLQQLLGELN YVRHKCRYDI NFAVKKVARL
    1601  VNYPHERVFY MIYKIIQYLV RYKDIGIHYD RDCNKDKKVI AITDASVGSE
    1651  YDAQSRIGVI LWYGMNIFNV YSNKSTNRCV SSTEAELHAI YEGYADSETL
    1701  KVTLKELGEG DNNDIVMITD SKPAIQGLNR SYQQPKEKFT WIKTEIIKEK
    1751  IKEKSIKLLK ITGKGNIADL LTKPVSASDF KRFIQVLKNK ITSQDILAST
    1801  DY*

external links for Yhl009w-bp

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YeastGFP
Pfam domains

References cited on this page View Complete Literature Guide for Yhl009w-bp

1)	Kim JM, et al. (1998) Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence. Genome Res 8(5):464-78
2)	Lesage P and Todeschini AL (2005) Happy together: the life and times of Ty retrotransposons and their hosts. Cytogenet Genome Res 110(1-4):70-90