YDR034C-D Protein Information

Systematic Name	Ydr034c-dp
Description	Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes (1, 2)

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	1,770
Molecular Weight (Da)	201,963
Isoelectric Point (pI)	8.34

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ydr034c-dp (InterPro)
Physical Interactions	There are 3 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000006B63D \| Q12472 NCBI: 1122355 \| 173115 \| 2058361 \| 3417407 \| 398365135 \| 74627281 \| NP_058138.3 GenBank/EMBL/DDBJ: DAA11879.1 \| M18805 \| Z68196 \| Z74330 \| Z74331
External Classifications	EC: 2.7.7.49 [RNA-directed DNA polymerase] EC: 2.7.7.7 [DNA-directed DNA polymerase] EC: 3.1.26.4 [Ribonuclease H] EC: 3.4.23.- [Aspartic Endopeptidases]

Amino Acid Sequence (or in FASTA format)
1 MESQQLSQNS PNLHGSAYAS VTSKEVPSNQ DPLAVSASNL PEFDRDSTKV 51 NSQQETTPGT SAVPENHHHV SPQPASVPPP QNGQYQQHGM MTPNKAMASN 101 WAHYQQPSMM TCSHYQTSPA YYQPDPHYPL PQYIPPLSTS SPDPIDLKNQ 151 HSEIPQAKTK VGNNVLPPHT LTSEENFSTW VKFYIRFLKN SNLGDIIPND 201 QGEIKRQMTY EEHAYIYNTF QAFAPFHLLP TWVKQILEIN YADILTVLCK 251 SVSKMQTNNQ ELKDWIALAN LEYDGSTSAD TFEITVSTII QRLKENNINV 301 SDRLACQLIL KGLSGDFKYL RNQYRTKTNM KLSQLFAEIQ LIYDENKIMN 351 LNKPSQYKQH SEYKNVSRTS PNTTNTKVTT RNYQRTNSSK PRAAKAHNIA 401 TSSKFSRVNN DHINESTVSS QYLSDDNELS LGQQQKESKP THTIDSNDEL 451 PDHLLIDSGA SQTLVRSAHY LHHATPNSEI NIVDAQKQDI PINAIGNLHF 501 NFQNGTKTSI KALHTPNIAY DLLSLSELAN QNITACFTRN TLERSDGTVL 551 APIVKHGDFY WLSKKYLIPS HISKLTINNV NKSKSVNKYP YPLIHRMLGH 601 ANFRSIQKSL KKNAVTYLKE SDIEWSNAST YQCPDCLIGK STKHRHVKGS 651 RLKYQESYEP FQYLHTDIFG PVHHLPKSAP SYFISFTDEK TRFQWVYPLH 701 DRREESILNV FTSILAFIKN QFNARVLVIQ MDRGSEYTNK TLHKFFTNRG 751 ITACYTTTAD SRAHGVAERL NRTLLNDCRT LLHCSGLPNH LWFSAVEFST 801 IIRNSLVSPK NDKSARQHAG LAGLDITTIL PFGQPVIVNN HNPDSKIHPR 851 GIPGYALHPS RNSYGYIIYL PSLKKTVDTT NYVILQDKQS KLDQFNYDTL 901 TFDDDLNRLT AHNQSFIEKN ETEQSYDQNT ESDHDYQSEI EINSDPLVND 951 FSSQSINPLQ LDKEPVQKVR APKEVDADIS EYNILPSTIR SRTPHIINKE 1001 STEMGGTIES DTTSPRHSST FTARNQKRPG SPNDMIDLTS QDRVNYGLEN 1051 IKTTRLGGTE EPYIQRNSDT NIKYRTTNST PSIDDRSSNS ESTTPIISIE 1101 TKAACDNTPS IDTDPPEYRS SDHATPNIMP DKSSKNVTAD SILDDLPLPD 1151 LTNKSPTDTS DVSKDIPHIH SRQTNSSLGG MDDSNVLTTT KSKKRSLEDN 1201 ETEIEVSRDT WNNKNMRSLE PPRSKKRINL IAAIKGVKSI KPVRTTLRYD 1251 EAITYNEDNK EKDRYIEAYH KEINQLLRMN TWDTNKYYDR NDIDPKKVIN 1301 SMFIFNKKRD GTHKARFVAR GDIQHPDTYD SDMQSNTVHH YALMTSLSIA 1351 LDNDYYITQL DISSAYLYAD IKEELYIRPP PHLGLNDKLL RLRKSLYGLK 1401 QSGANWYETI KSYLINCCDM QEVRGWSCVF KNSQVTICLF VDDMILFSKD 1451 LNANKKIITT LKKQYDTKII NLGEGDNEIQ YDILGLEIKY QRSKYMKLGM 1501 EKSLTEKLPK LNVPLNPKGK KLRAPGQPGH YIDQDELEID EDEYKEKVHE 1551 MQKLIGLASY VGYKFRFDLL YYINTLAQHI LFPSRQVLDM TYELIQFMWD 1601 TRDKQLIWHK NKPTKPDNKL VAISDASYGN QPYYKSQIGN IFLLNGKVIG 1651 GKSTKASLTC TSTTEAEIHA VSEAIPLLNN LSHLVQELNK KPIIKGLLTD 1701 SRSTISIIKS TNEEKFRNRF FGTKAMRLRD EVSGNNLYVY YIETKKNIAD 1751 VMTKPLPIKT FKLLTNKWIH *

Amino Acid Sequence (or in FASTA format)

       1  MESQQLSQNS PNLHGSAYAS VTSKEVPSNQ DPLAVSASNL PEFDRDSTKV
      51  NSQQETTPGT SAVPENHHHV SPQPASVPPP QNGQYQQHGM MTPNKAMASN
     101  WAHYQQPSMM TCSHYQTSPA YYQPDPHYPL PQYIPPLSTS SPDPIDLKNQ
     151  HSEIPQAKTK VGNNVLPPHT LTSEENFSTW VKFYIRFLKN SNLGDIIPND
     201  QGEIKRQMTY EEHAYIYNTF QAFAPFHLLP TWVKQILEIN YADILTVLCK
     251  SVSKMQTNNQ ELKDWIALAN LEYDGSTSAD TFEITVSTII QRLKENNINV
     301  SDRLACQLIL KGLSGDFKYL RNQYRTKTNM KLSQLFAEIQ LIYDENKIMN
     351  LNKPSQYKQH SEYKNVSRTS PNTTNTKVTT RNYQRTNSSK PRAAKAHNIA
     401  TSSKFSRVNN DHINESTVSS QYLSDDNELS LGQQQKESKP THTIDSNDEL
     451  PDHLLIDSGA SQTLVRSAHY LHHATPNSEI NIVDAQKQDI PINAIGNLHF
     501  NFQNGTKTSI KALHTPNIAY DLLSLSELAN QNITACFTRN TLERSDGTVL
     551  APIVKHGDFY WLSKKYLIPS HISKLTINNV NKSKSVNKYP YPLIHRMLGH
     601  ANFRSIQKSL KKNAVTYLKE SDIEWSNAST YQCPDCLIGK STKHRHVKGS
     651  RLKYQESYEP FQYLHTDIFG PVHHLPKSAP SYFISFTDEK TRFQWVYPLH
     701  DRREESILNV FTSILAFIKN QFNARVLVIQ MDRGSEYTNK TLHKFFTNRG
     751  ITACYTTTAD SRAHGVAERL NRTLLNDCRT LLHCSGLPNH LWFSAVEFST
     801  IIRNSLVSPK NDKSARQHAG LAGLDITTIL PFGQPVIVNN HNPDSKIHPR
     851  GIPGYALHPS RNSYGYIIYL PSLKKTVDTT NYVILQDKQS KLDQFNYDTL
     901  TFDDDLNRLT AHNQSFIEKN ETEQSYDQNT ESDHDYQSEI EINSDPLVND
     951  FSSQSINPLQ LDKEPVQKVR APKEVDADIS EYNILPSTIR SRTPHIINKE
    1001  STEMGGTIES DTTSPRHSST FTARNQKRPG SPNDMIDLTS QDRVNYGLEN
    1051  IKTTRLGGTE EPYIQRNSDT NIKYRTTNST PSIDDRSSNS ESTTPIISIE
    1101  TKAACDNTPS IDTDPPEYRS SDHATPNIMP DKSSKNVTAD SILDDLPLPD
    1151  LTNKSPTDTS DVSKDIPHIH SRQTNSSLGG MDDSNVLTTT KSKKRSLEDN
    1201  ETEIEVSRDT WNNKNMRSLE PPRSKKRINL IAAIKGVKSI KPVRTTLRYD
    1251  EAITYNEDNK EKDRYIEAYH KEINQLLRMN TWDTNKYYDR NDIDPKKVIN
    1301  SMFIFNKKRD GTHKARFVAR GDIQHPDTYD SDMQSNTVHH YALMTSLSIA
    1351  LDNDYYITQL DISSAYLYAD IKEELYIRPP PHLGLNDKLL RLRKSLYGLK
    1401  QSGANWYETI KSYLINCCDM QEVRGWSCVF KNSQVTICLF VDDMILFSKD
    1451  LNANKKIITT LKKQYDTKII NLGEGDNEIQ YDILGLEIKY QRSKYMKLGM
    1501  EKSLTEKLPK LNVPLNPKGK KLRAPGQPGH YIDQDELEID EDEYKEKVHE
    1551  MQKLIGLASY VGYKFRFDLL YYINTLAQHI LFPSRQVLDM TYELIQFMWD
    1601  TRDKQLIWHK NKPTKPDNKL VAISDASYGN QPYYKSQIGN IFLLNGKVIG
    1651  GKSTKASLTC TSTTEAEIHA VSEAIPLLNN LSHLVQELNK KPIIKGLLTD
    1701  SRSTISIIKS TNEEKFRNRF FGTKAMRLRD EVSGNNLYVY YIETKKNIAD
    1751  VMTKPLPIKT FKLLTNKWIH *

external links for Ydr034c-dp

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YeastGFP
Pfam domains

References cited on this page View Complete Literature Guide for Ydr034c-dp

1)	Kim JM, et al. (1998) Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence. Genome Res 8(5):464-78
2)	Lesage P and Todeschini AL (2005) Happy together: the life and times of Ty retrotransposons and their hosts. Cytogenet Genome Res 110(1-4):70-90