COX2/Q0250 Protein Information

Standard Name	Cox2p
Systematic Name	Q0250p
Alias	Oxi1p , Oxiip
ORF Classification	Verified
Description	Subunit II of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits (1)
Name Description	Cytochrome c OXidase

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	251
Molecular Weight (Da)	28,567
Isoelectric Point (pI)	4.28

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Cox2p (InterPro)
Transmembrane Domains	There are 2 total predicted transmembrane domains (TMHMM)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 45 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000128097 \| P00410 MIPS: Q0250 NCBI: 117050 \| 13512 \| 13613 \| 2160325 \| 4160387 \| 567912 \| 6226540 \| 7145101 \| 7537358 \| NP_009326.1 GenBank/EMBL/DDBJ: AJ011856 \| D55725 \| J05007 \| K02200 \| L36888 \| V00685 \| V00706
External Classifications	EC: 1.9.3.1 [Cytochrome-c oxidase]

Amino Acid Sequence (or in FASTA format)
1 MLDLLRLQLT TFIMNDVPTP YACYFQDSAT PNQEGILELH DNIMFYLLVI 51 LGLVSWMLYT IVMTYSKNPI AYKYIKHGQT IEVIWTIFPA VILLIIAFPS 101 FILLYLCDEV ISPAMTIKAI GYQWYWKYEY SDFINDSGET VEFESYVIPD 151 ELLEEGQLRL LDTDTSMVVP VDTHIRFVVT AADVIHDFAI PSLGIKVDAT 201 PGRLNQVSAL IQREGVFYGA CSELCGTGHA NMPIKIEAVS LPKFLEWLNE 251 Q*

Amino Acid Sequence (or in FASTA format)

       1  MLDLLRLQLT TFIMNDVPTP YACYFQDSAT PNQEGILELH DNIMFYLLVI
      51  LGLVSWMLYT IVMTYSKNPI AYKYIKHGQT IEVIWTIFPA VILLIIAFPS
     101  FILLYLCDEV ISPAMTIKAI GYQWYWKYEY SDFINDSGET VEFESYVIPD
     151  ELLEEGQLRL LDTDTSMVVP VDTHIRFVVT AADVIHDFAI PSLGIKVDAT
     201  PGRLNQVSAL IQREGVFYGA CSELCGTGHA NMPIKIEAVS LPKFLEWLNE
     251  Q*

external links for Cox2p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS
YGOB	CYC2008 (complexes)	Pfam domains
YOGY	Complexome
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Cox2p

1)	Taanman JW and Capaldi RA (1992) Purification of yeast cytochrome c oxidase with a subunit composition resembling the mammalian enzyme. J Biol Chem 267(31):22481-5