VAR1/Q0140 Protein Information

Standard Name	Var1p
Systematic Name	Q0140p
ORF Classification	Verified
Description	Mitochondrial ribosomal protein of the small subunit, mitochondrially-encoded; polymorphic in different strains due to variation in number of AAT (asparagine) codons; translated near the mitochondrial inner membrane (1, 2, 3, 4) Also known as: VARI

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	398
Molecular Weight (Da)	47,123
Isoelectric Point (pI)	10.75

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Var1p (InterPro)
Physical Interactions	There are 9 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000009062C \| P02381 MIPS: Q0140 NCBI: 116242761 \| 13611 \| 3452511 \| 4160381 \| 50403706 \| 567922 \| 6226534 \| NP_009320.1 GenBank/EMBL/DDBJ: AJ010480 \| AJ011856 \| L36900 \| V00705

Amino Acid Sequence (or in FASTA format)
1 MKLKLLNMIL SMMNKTNNNN NIIINNTLDS LMNKKLLLKN MLLDMNNKKM 51 NNMKRMLNNN NMNPAGANPV VHRIGPAGNI NNKLQHLNNM NNWNTQIYNY 101 NKNMEIMNTM NDKLINKLLY KMMTLKLNNM NINKIIMSKT INQHSLNKLN 151 IKFYYYNNDI NNNNNNNNNN YYMNMMNKLM NIMNNNMNNN LCNILSYYYK 201 KKVTIEPIKL SYIYLNSDIF SKYISLNDMD KYNNGILTNY QRMLNNIMPK 251 LNDHNISMNY INNINNINNN KYNNMINLLN NNNNINNNNN YNNNNNNYIG 301 NINNIYNNMT IDNIPMDILM YKYLVGWSIK FKGRLSNNNG RTSTTNLLNG 351 TFNNKKYLWS NINNNYKLNY IPSNHNLYNN SNINKNGKYN IKVKLNFI*

Amino Acid Sequence (or in FASTA format)

       1  MKLKLLNMIL SMMNKTNNNN NIIINNTLDS LMNKKLLLKN MLLDMNNKKM
      51  NNMKRMLNNN NMNPAGANPV VHRIGPAGNI NNKLQHLNNM NNWNTQIYNY
     101  NKNMEIMNTM NDKLINKLLY KMMTLKLNNM NINKIIMSKT INQHSLNKLN
     151  IKFYYYNNDI NNNNNNNNNN YYMNMMNKLM NIMNNNMNNN LCNILSYYYK
     201  KKVTIEPIKL SYIYLNSDIF SKYISLNDMD KYNNGILTNY QRMLNNIMPK
     251  LNDHNISMNY INNINNINNN KYNNMINLLN NNNNINNNNN YNNNNNNYIG
     301  NINNIYNNMT IDNIPMDILM YKYLVGWSIK FKGRLSNNNG RTSTTNLLNG
     351  TFNNKKYLWS NINNNYKLNY IPSNHNLYNN SNINKNGKYN IKVKLNFI*

external links for Var1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome
	GeneMANIA

References cited on this page View Complete Literature Guide for Var1p

1)	Groot GS, et al. (1979) Var1 is associated with the small ribosomal subunit of mitochondrial ribosomes in yeast. Mol Gen Genet 174(3):339-42
2)	Hudspeth ME, et al. (1982) Location and structure of the var1 gene on yeast mitochondrial DNA: nucleotide sequence of the 40.0 allele. Cell 30(2):617-26
3)	Hudspeth ME, et al. (1984) Expandable var1 gene of yeast mitochondrial DNA: in-frame insertions can explain the strain-specific protein size polymorphisms. Proc Natl Acad Sci U S A 81(10):3148-52
4)	Fiori A, et al. (2003) Evidence that synthesis of the Saccharomyces cerevisiae mitochondrially encoded ribosomal protein Var1p may be membrane localized. Eukaryot Cell 2(3):651-3