BI4/Q0120 Protein Information

Standard Name	Bi4p
Systematic Name	Q0120p
ORF Classification	Verified
Description	Mitochondrial mRNA maturase, forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA (1)

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	638
Molecular Weight (Da)	74,580
Isoelectric Point (pI)	10.46

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Bi4p (InterPro)
Transmembrane Domains	There are 7 total predicted transmembrane domains (TMHMM)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 7 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000008F67F \| P03879 MIPS: Q0120 NCBI: 4160379 \| 4837715 \| 4837716 \| 50403711 \| 6226532 \| 7550151 \| NP_009316.1 \| NM_001184365.1 GenBank/EMBL/DDBJ: AJ011856 \| S76640 \| V00696
External Classifications	EC: 3.1.-.- [Hydrolases acting on ester bonds ]

Amino Acid Sequence (or in FASTA format)
1 MAFRKSNVYL SLVNSYIIDS PQPSSINYWW NMGSLLGLCL VIQIVTGIFM 51 AMHYSSNIEL AFSSVEHIMR DVHNGYILRY LHANGASFFF MVMFMHMAKG 101 LYYGSYRSPR VTLWNVGVII FILTIATAFL GYCCVYGQMS HWGATVITNL 151 FSAIPFVGND IVSWLWGGFS VSNPTIQRFF ALHYLVPFII AAMVIMHLMA 201 LHIHGSSNPL GITGNLDRIP MHSYFIFKDL VTVFLFMLIL ALFVFYSPNT 251 LGQNMALLLI TYVINILCAV CWKSLFIKYQ WKIYNKTTYY FIIQNILNTK 301 QLNNFVLKFN WTKQYNKMNI VSDLFNPNRV KYYYKEDNQQ VTNMNSSNTH 351 LTSNKKNLLV DTSETTRTTK NKFNYLLNIF NMKKMNQIIT KRHYSIYKDS 401 NIRFNQWLAG LIDGDGYFCI TKNKYASCEI TVELKDEKML RQIQDKFGGS 451 VKLRSGVKAI RYRLQNKEGM IKLINAVNGN IRNSKRLVQF NKVCILLNID 501 FKEPIKLTKD NAWFMGFFDA DGTINYYYSG KLKIRPQLTI SVTNKYLHDV 551 EYYREVFGGN IYFDKAKNGY FKWSINNKEL HNIFYTYNKS CPSKSNKGKR 601 LFLIDKFYYL YDLLAFKAPH NTALYKAWLK FNEKWNNN*

Amino Acid Sequence (or in FASTA format)

       1  MAFRKSNVYL SLVNSYIIDS PQPSSINYWW NMGSLLGLCL VIQIVTGIFM
      51  AMHYSSNIEL AFSSVEHIMR DVHNGYILRY LHANGASFFF MVMFMHMAKG
     101  LYYGSYRSPR VTLWNVGVII FILTIATAFL GYCCVYGQMS HWGATVITNL
     151  FSAIPFVGND IVSWLWGGFS VSNPTIQRFF ALHYLVPFII AAMVIMHLMA
     201  LHIHGSSNPL GITGNLDRIP MHSYFIFKDL VTVFLFMLIL ALFVFYSPNT
     251  LGQNMALLLI TYVINILCAV CWKSLFIKYQ WKIYNKTTYY FIIQNILNTK
     301  QLNNFVLKFN WTKQYNKMNI VSDLFNPNRV KYYYKEDNQQ VTNMNSSNTH
     351  LTSNKKNLLV DTSETTRTTK NKFNYLLNIF NMKKMNQIIT KRHYSIYKDS
     401  NIRFNQWLAG LIDGDGYFCI TKNKYASCEI TVELKDEKML RQIQDKFGGS
     451  VKLRSGVKAI RYRLQNKEGM IKLINAVNGN IRNSKRLVQF NKVCILLNID
     501  FKEPIKLTKD NAWFMGFFDA DGTINYYYSG KLKIRPQLTI SVTNKYLHDV
     551  EYYREVFGGN IYFDKAKNGY FKWSINNKEL HNIFYTYNKS CPSKSNKGKR
     601  LFLIDKFYYL YDLLAFKAPH NTALYKAWLK FNEKWNNN*

external links for Bi4p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome
	GeneMANIA

References cited on this page View Complete Literature Guide for Bi4p

1)	Rho SB and Martinis SA (2000) The bI4 group I intron binds directly to both its protein splicing partners, a tRNA synthetase and maturase, to facilitate RNA splicing activity. RNA 6(12):1882-94