COB/Q0105 Protein Information

Standard Name	Cobp
Systematic Name	Q0105p
Alias	Cob1p , Cytbp
ORF Classification	Verified
Description	Cytochrome b, mitochondrially encoded subunit of the ubiquinol-cytochrome c reductase complex which includes Cobp, Rip1p, Cyt1p, Cor1p, Qcr2p, Qcr6p, Qcr7p, Qcr8p, Qcr9p, and Qcr10p (1, 2)
Name Description	CytochrOme B

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	385
Molecular Weight (Da)	43,656
Isoelectric Point (pI)	9.24

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Cobp (InterPro)
Transmembrane Domains	There are 9 total predicted transmembrane domains (TMHMM)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 20 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000009099B \| P00163 MIPS: Q0105 NCBI: 14277714 \| 145579628 \| 188036282 \| 188036293 \| 188036305 \| 188036316 \| 20151120 \| 20151131 \| 24158773 \| 30179770 \| 34811038 \| 4160376 \| 6226529 \| 643021 \| 7537354 \| 7537355 \| NP_009315.1 GenBank/EMBL/DDBJ: AJ011856 \| J01472 \| J01473 \| J01474 \| J01475 \| V00696 \| X84042

Amino Acid Sequence (or in FASTA format)
1 MAFRKSNVYL SLVNSYIIDS PQPSSINYWW NMGSLLGLCL VIQIVTGIFM 51 AMHYSSNIEL AFSSVEHIMR DVHNGYILRY LHANGASFFF MVMFMHMAKG 101 LYYGSYRSPR VTLWNVGVII FILTIATAFL GYCCVYGQMS HWGATVITNL 151 FSAIPFVGND IVSWLWGGFS VSNPTIQRFF ALHYLVPFII AAMVIMHLMA 201 LHIHGSSNPL GITGNLDRIP MHSYFIFKDL VTVFLFMLIL ALFVFYSPNT 251 LGHPDNYIPG NPLVTPASIV PEWYLLPFYA ILRSIPDKLL GVITMFAAIL 301 VLLVLPFTDR SVVRGNTFKV LSKFFFFIFV FNFVLLGQIG ACHVEVPYVL 351 MGQIATFIYF AYFLIIVPVI STIENVLFYI GRVNK*

Amino Acid Sequence (or in FASTA format)

       1  MAFRKSNVYL SLVNSYIIDS PQPSSINYWW NMGSLLGLCL VIQIVTGIFM
      51  AMHYSSNIEL AFSSVEHIMR DVHNGYILRY LHANGASFFF MVMFMHMAKG
     101  LYYGSYRSPR VTLWNVGVII FILTIATAFL GYCCVYGQMS HWGATVITNL
     151  FSAIPFVGND IVSWLWGGFS VSNPTIQRFF ALHYLVPFII AAMVIMHLMA
     201  LHIHGSSNPL GITGNLDRIP MHSYFIFKDL VTVFLFMLIL ALFVFYSPNT
     251  LGHPDNYIPG NPLVTPASIV PEWYLLPFYA ILRSIPDKLL GVITMFAAIL
     301  VLLVLPFTDR SVVRGNTFKV LSKFFFFIFV FNFVLLGQIG ACHVEVPYVL
     351  MGQIATFIYF AYFLIIVPVI STIENVLFYI GRVNK*

external links for Cobp

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS
Candida (CGD)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Cobp

1)	Hunte C, et al. (2000) Structure at 2.3 A resolution of the cytochrome bc(1) complex from the yeast Saccharomyces cerevisiae co-crystallized with an antibody Fv fragment. Structure 8(6):669-84
2)	Kreike J, et al. (1979) The identification of apocytochrome b as a mitochondrial gene product and immunological evidence for altered apocytochrome b in yeast strains having mutations in the COB region of mitochondrial DNA. Eur J Biochem 101(2):607-17