AI5_ALPHA/Q0070 Protein Information Help

Standard Name Ai5_alphap
Systematic Name Q0070p
ORF Classification Verified
Description Endonuclease I-SceIV, involved in intron mobility; encoded by a mobile group I intron within the mitochondrial COX1 gene (1, 2)
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 630
Molecular Weight (Da) 72,164
Isoelectric Point (pI) 10.35

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ai5_alphap (InterPro)
Transmembrane Domains There are 10 total predicted transmembrane domains (TMHMM)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 1 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000091C05 | Q9ZZX1
MIPS: Q0070
NCBI: 17939864 | 4160371 | 6226524 | 74698620 | NP_009306.1
GenBank/EMBL/DDBJ: AJ011856
External Classifications EC: 3.1.-.- [Hydrolases acting on ester bonds ]
Amino Acid Sequence (or in FASTA format)
 
       1  MVQRWLYSTN AKDIAVLYFM LAIFSGMAGT AMSLIIRLEL AAPGSQYLHG
      51  NSQLFNVLVV GHAVLMIFFL VMPALIGGFG NYLLPLMIGA TDTAFPRINN
     101  IAFWVLPMGL VCLVTSTLVE SGAGTGWTVY PPLSSIQAHS GPSVDLAIFA
     151  LHLTSISSLL GAINFIVTTL NMRTNGMTMH KLPLFVWSIF ITAFLLLLSL
     201  PVLSAGITML LLDRNFNTSF FEVSGGGDPI LYEHLFWFFG HPEVYILIIP
     251  GFGIISHVVS TYSKKPVFGE ISMVYAMASI GLLGFLVWSH HMYIVGLDAD
     301  TRAYFTSATM IIAIPTGIKI FSWLMNPFSK DKNKNKNKKL IRNYQKMNNN
     351  NMMKTYLNNN NMIMMNMYKG NLYDIYPRSN RNYIQPNNIN KELVVYGYNL
     401  ESCVGMPTYT NIVKHMVGIP NNILYIMTGI LLTDGWIDYT SKKDLDKKTI
     451  MEINCRFRLK QSMIHSEYLM YVFMLLSHYC MSYPKMKIAK VKGKSYNQLE
     501  FYTRSLPCFT ILRYMFYNGR VKIVPNNLYD LLNYESLAHM IMCDGSFVKG
     551  GGLYLNLQSF TTKELIFIMN ILKIKFNLNC TLHKSRNKYT IYMRVESVKR
     601  LFPMIYKYIL PSMRYKFDIM LWQKKYNMIN *

external links for Ai5_alphap
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS
YOGY CYC2008 (complexes) Pfam domains

Complexome


GeneMANIA

References cited on this page View Complete Literature Guide for Ai5_alphap
1) Seraphin B, et al.  (1992) The yeast mitochondrial intron aI5 alpha: associated endonuclease activity and in vivo mobility. Gene 113(1):1-8
2) Wernette CM  (1998) Structure and activity of the mitochondrial intron-encoded endonuclease, I-SceIV. Biochem Biophys Res Commun 248(1):127-33