AI2/Q0055 Protein Information Help

Standard Name Ai2p
Systematic Name Q0055p
ORF Classification Verified
Description Reverse transcriptase required for splicing of the COX1 pre-mRNA, encoded by a mobile group II intron within the mitochondrial COX1 gene (1, 2, 3)
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 854
Molecular Weight (Da) 98,008
Isoelectric Point (pI) 10.45

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ai2p (InterPro)
Transmembrane Domains There are 3 total predicted transmembrane domains (TMHMM)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 1 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000091E11 | P03876
MIPS: Q0055
NCBI: 1334435 | 4160368 | 6226521 | 84028171 | NP_009309.1
GenBank/EMBL/DDBJ: AJ011856 | V00694
Amino Acid Sequence (or in FASTA format)
 
       1  MVQRWLYSTN AKDIAVLYFM LAIFSGMAGT AMSLIIRLEL AAPGSQYLHG
      51  NSQLFNVLVV GHAVLMIFCA PFRLIYHCIE VLIDKHISVY SINENFTVSF
     101  WFWLLVVTYM VFRYVNHMAY PVGANSTGTM ACHKSAGVKQ PAQGKNCPMA
     151  RLTNSCKECL GFSLTPSHLG IVIHAYVLEE EVHELTKNES LALSKSWHLE
     201  GCTSSNGKLR NTGLSERGNP GDNGVFMVPK FNLNKVRYFS TLSKLNARKE
     251  DSLAYLTKIN TTDFSELNKL MENNHNKTET INTRILKLMS DIRMLLIAYN
     301  KIKSKKGNMS KGSNNITLDG INISYLNKLS KDINTNMFKF SPVRRVEIPK
     351  TSGGFRPLSV GNPREKIVQE SMRMMLEIIY NNSFSYYSHG FRPNLSCLTA
     401  IIQCKNYMQY CNWFIKVDLN KCFDTIPHNM LINVLNERIK DKGFMDLLYK
     451  LLRAGYVDKN NNYHNTTLGI PQGSVVSPIL CNIFLDKLDK YLENKFENEF
     501  NTGNMSNRGR NPIYNSLSSK IYRCKLLSEK LKLIRLRDHY QRNMGSDKSF
     551  KRAYFVRYAD DIIIGVMGSH NDCKNILNDI NNFLKENLGM SINMDKSVIK
     601  HSKEGVSFLG YDVKVTPWEK RPYRMIKKGD NFIRVRHHTS LVVNAPIRSI
     651  VMKLNKHGYC SHGILGKPRG VGRLIHEEMK TILMHYLAVG RGIMNYYRLA
     701  TNFTTLRGRI TYILFYSCCL TLARKFKLNT VKKVILKFGK VLVDPHSKVS
     751  FSIDDFKIRH KMNMTDSNYT PDEILDRYKY MLPRSLSLFS GICQICGSKH
     801  DLEVHHVRTL NNAANKIKDD YLLGRMIKMN RKQITICKTC HFKVHQGKYN
     851  GPGL*

external links for Ai2p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS
YOGY CYC2008 (complexes) Pfam domains

Complexome


GeneMANIA

References cited on this page View Complete Literature Guide for Ai2p
1) Moran JV, et al.  (1994) Splicing defective mutants of the COXI gene of yeast mitochondrial DNA: initial definition of the maturase domain of the group II intron aI2. Nucleic Acids Res 22(11):2057-64
2) Kennell JC, et al.  (1993) Reverse transcriptase activity associated with maturase-encoding group II introns in yeast mitochondria. Cell 73(1):133-46
3) Moran JV, et al.  (1995) Mobile group II introns of yeast mitochondrial DNA are novel site-specific retroelements. Mol Cell Biol 15(5):2828-38