AI1/Q0050 Protein Information Help

Standard Name Ai1p
Systematic Name Q0050p
ORF Classification Verified
Description Reverse transcriptase required for splicing of the COX1 pre-mRNA, encoded by a mobile group II intron within the mitochondrial COX1 gene (1, 2, 3)
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 834
Molecular Weight (Da) 96,078
Isoelectric Point (pI) 10.7

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ai1p (InterPro)
Transmembrane Domains There are 1 total predicted transmembrane domains (TMHMM)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 6 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000097281 | P03875
MIPS: Q0050
NCBI: 1334433 | 4160367 | 567917 | 6226520 | 84028170 | NP_009310.1
GenBank/EMBL/DDBJ: AJ011856 | L36897 | V00694
Amino Acid Sequence (or in FASTA format)
 
       1  MVQRWLYSTN AKDIAVLYFM LAIFSGMAGT AMSLIIRLEL AAPGSQYLHG
      51  NSQLFNGAPT SAYISLMRTA LVLWIINRYL KHMTNSVGAN FTGTMACHKT
     101  PMISVGGVKC YMVRLTNFLQ VFIRITISSY HLDMVKQVWL FYVEVIRLWF
     151  IVLDSTGSVK KMKDTNNTKG NTKSEGSTER GNSGVDRGMV VPNTQMKMRF
     201  LNQVRYYSVN NNLKMGKDTN IELSKDTSTS DLLEFEKLVM DNMNEENMNN
     251  NLLSIMKNVD MLMLAYNRIK SKPGNMTPGT TLETLDGMNM MYLNKLSNEL
     301  GTGKFKFKPM RMVNIPKPKG GMRPLSVGNP RDKIVQEVMR MILDTIFDKK
     351  MSTHSHGFRK NMSCQTAIWE VRNMFGGSNW FIEVDLKKCF DTISHDLIIK
     401  ELKRYISDKG FIDLVYKLLR AGYIDEKGTY HKPMLGLPQG SLISPILCNI
     451  VMTLVDNWLE DYINLYNKGK VKKQHPTYKK LSRMIAKAKM FSTRLKLHKE
     501  RAKGPTFIYN DPNFKRMKYV RYADDILIGV LGSKNDCKMI KRDLNNFLNS
     551  LGLTMNEEKT LITCATETPA RFLGYNISIT PLKRMPTVTK TIRGKTIRSR
     601  NTTRPIINAP IRDIINKLAT NGYCKHNKNG RMGVPTRVGR WTYEEPRTII
     651  NNYKALGRGI LNYYKLATNY KRLRERIYYV LYYSCVLTLA SKYRLKTMSK
     701  TIKKFGYNLN IIENDKLIAN FPRNTFDNIK KIENHGMFMY MSEAKVTDPF
     751  EYIDSIKYML PTAKANFNKP CSICNSTIDV EMHHVKQLHR GMLKATKDYI
     801  TGRMITMNRK QIPLCKQCHI KTHKNKFKNM GPGM*

external links for Ai1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS
YOGY CYC2008 (complexes) Pfam domains

Complexome


DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Ai1p
1) Moran JV, et al.  (1994) Splicing defective mutants of the COXI gene of yeast mitochondrial DNA: initial definition of the maturase domain of the group II intron aI2. Nucleic Acids Res 22(11):2057-64
2) Kennell JC, et al.  (1993) Reverse transcriptase activity associated with maturase-encoding group II introns in yeast mitochondria. Cell 73(1):133-46
3) Moran JV, et al.  (1995) Mobile group II introns of yeast mitochondrial DNA are novel site-specific retroelements. Mol Cell Biol 15(5):2828-38