COX1/Q0045 Protein Information Help

Standard Name Cox1p
Systematic Name Q0045p
Alias Oxi3p
ORF Classification Verified
Description Subunit I of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits (1)
Name Description Cytochrome c OXidase
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 534
Molecular Weight (Da) 58,798
Isoelectric Point (pI) 7.12

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Cox1p (InterPro)
Transmembrane Domains There are 12 total predicted transmembrane domains (TMHMM)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 53 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000095A7E | P00401
MIPS: Q0045
NCBI: 13585 | 30179802 | 4160366 | 6226519 | NP_009305.1
GenBank/EMBL/DDBJ: AJ011856 | V00694 | X14910
External Classifications EC: 1.9.3.1 [Cytochrome-c oxidase]
Amino Acid Sequence (or in FASTA format)
 
       1  MVQRWLYSTN AKDIAVLYFM LAIFSGMAGT AMSLIIRLEL AAPGSQYLHG
      51  NSQLFNVLVV GHAVLMIFFL VMPALIGGFG NYLLPLMIGA TDTAFPRINN
     101  IAFWVLPMGL VCLVTSTLVE SGAGTGWTVY PPLSSIQAHS GPSVDLAIFA
     151  LHLTSISSLL GAINFIVTTL NMRTNGMTMH KLPLFVWSIF ITAFLLLLSL
     201  PVLSAGITML LLDRNFNTSF FEVSGGGDPI LYEHLFWFFG HPEVYILIIP
     251  GFGIISHVVS TYSKKPVFGE ISMVYAMASI GLLGFLVWSH HMYIVGLDAD
     301  TRAYFTSATM IIAIPTGIKI FSWLATIHGG SIRLATPMLY AIAFLFLFTM
     351  GGLTGVALAN ASLDVAFHDT YYVVGHFHYV LSMGAIFSLF AGYYYWSPQI
     401  LGLNYNEKLA QIQFWLIFIG ANVIFFPMHF LGINGMPRRI PDYPDAFAGW
     451  NYVASIGSFI ATLSLFLFIY ILYDQLVNGL NNKVNNKSVI YNKAPDFVES
     501  NTIFNLNTVK SSSIEFLLTS PPAVHSFNTP AVQS*

external links for Cox1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Candida (CGD) BioPIXIE MIPS
YGOB CYC2008 (complexes) Pfam domains
YOGY Complexome


GeneMANIA

References cited on this page View Complete Literature Guide for Cox1p
1) Taanman JW and Capaldi RA  (1992) Purification of yeast cytochrome c oxidase with a subunit composition resembling the mammalian enzyme. J Biol Chem 267(31):22481-5