HUB1/YNR032C-A Protein Information 
| Standard Name | Hub1p 1 |
|---|---|
| Systematic Name | Ynr032c-ap |
| ORF Classification | Verified |
| Description | Ubiquitin-like protein modifier; promotes alternative splicing of SRC1 pre-mRNA; binds non-covalently to the HIND domain of Snu66, may function in modification of Sph1p and Hbt1p, functionally complemented by the human or S. pombe ortholog; mechanism of Hub1p adduct formation not yet clear (1, 2, 3, 4) |
| Name Description | Homologous to UBiquitin |
| Click on image for expanded interactive view |
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| Post-translational Modifications | PhosphoGRID | PhosphoPep Database |
|---|---|
| Domains/motifs | See the graphical view and list of proteins that share domains/motifs in common with Hub1p (InterPro) |
| Physical Interactions | There are 15 total physical interactions (BioGRID) |
| Homologs | PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer |
| External Sequence Databases |
EBI: UPI0000168403 | Q6Q546 MIPS: YNR032C-A NCBI: 27573859 | 334359249 | 334359250 | 334359253 | 45271008 | 6324360 | 83305829 | NP_014430.1 | NM_001184344.1 GenBank/EMBL/DDBJ: DAA10573.1 | AY558559 | Z71648 |
external links for Hub1p
| Homologs | Interaction Resources | Protein databases/Other | Localization Resources |
|---|---|---|---|
| BLASTP (NCBI) | BioGRID | SCOP Superfamily | YPL+ |
| Ashbya (AGD) | BOND | GPMdb (Mass Spec.) | YeastGFP |
| Candida (CGD) | BioPIXIE | MIPS | |
| Candida (CandidaDB) | CYC2008 (complexes) | Pfam domains | |
| YGOB | Complexome | YeastRC Structure Prediction (Seattle) | |
| YOGY | GeneMANIA | ||
| YeastRC Two-Hybrid (Seattle) |
References cited on this page View Complete Literature Guide for Hub1p
| 1) | Dittmar GA, et al. (2002) Role of a ubiquitin-like modification in polarized morphogenesis. Science 295(5564):2442-6 |
| 2) | McNally T, et al. (2003) Structural analysis of UBL5, a novel ubiquitin-like modifier. Protein Sci 12(7):1562-6 |
| 3) | Luders J, et al. (2003) The ubiquitin-like protein HUB1 forms SDS-resistant complexes with cellular proteins in the absence of ATP. EMBO Rep 4(12):1169-74 |
| 4) | Mishra SK, et al. (2011) Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing. Nature () |
