RHO1/YPR165W Protein Information

Standard Name	Rho1p 1
Systematic Name	Ypr165wp
ORF Classification	Verified
Description	GTP-binding protein of the rho subfamily of Ras-like proteins, involved in establishment of cell polarity; regulates protein kinase C (Pkc1p) and the cell wall synthesizing enzyme 1,3-beta-glucan synthase (Fks1p and Gsc2p) (2, 3, 4)
Name Description	Ras HOmolog 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	209
Molecular Weight (Da)	23,152
Isoelectric Point (pI)	6.07

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rho1p (InterPro)
Physical Interactions	There are 75 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000133887 \| P06780 MIPS: YPR165W NCBI: 132536 \| 171977 \| 172420 \| 283806827 \| 283806829 \| 283806831 \| 45270014 \| 6325423 \| 786290 \| NP_015491.1 GenBank/EMBL/DDBJ: DAA11582.1 \| AY558062 \| M15161 \| M15189 \| U25840

Amino Acid Sequence (or in FASTA format)
1 MSQQVGNSIR RKLVIVGDGA CGKTCLLIVF SKGQFPEVYV PTVFENYVAD 51 VEVDGRRVEL ALWDTAGQED YDRLRPLSYP DSNVVLICFS IDLPDSLENV 101 QEKWIAEVLH FCQGVPIILV GCKVDLRNDP QTIEQLRQEG QQPVTSQEGQ 151 SVADQIGATG YYECSAKTGY GVREVFEAAT RASLMGKSKT NGKAKKNTTE 201 KKKKKCVLL*

Amino Acid Sequence (or in FASTA format)

       1  MSQQVGNSIR RKLVIVGDGA CGKTCLLIVF SKGQFPEVYV PTVFENYVAD
      51  VEVDGRRVEL ALWDTAGQED YDRLRPLSYP DSNVVLICFS IDLPDSLENV
     101  QEKWIAEVLH FCQGVPIILV GCKVDLRNDP QTIEQLRQEG QQPVTSQEGQ
     151  SVADQIGATG YYECSAKTGY GVREVFEAAT RASLMGKSKT NGKAKKNTTE
     201  KKKKKCVLL*

external links for Rho1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Rho1p

1)	Madaule P, et al. (1987) Characterization of two members of the rho gene family from the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 84(3):779-83
2)	Drgonova J, et al. (1999) The GTP-binding protein Rho1p is required for cell cycle progression and polarization of the yeast cell. J Cell Biol 146(2):373-87
3)	Drgonova J, et al. (1996) Rho1p, a yeast protein at the interface between cell polarization and morphogenesis. Science 272(5259):277-9
4)	Qadota H, et al. (1996) Identification of yeast Rho1p GTPase as a regulatory subunit of 1,3-beta-glucan synthase. Science 272(5259):279-81