NCE102/YPR149W Protein Information

Standard Name	Nce102p
Systematic Name	Ypr149wp
Alias	Nce2p 1
ORF Classification	Verified
Description	Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs); NCE102 has a paralog, FHN1, that arose from the whole genome duplication (1, 2, 3)
Name Description	NonClassical Export 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	173
Molecular Weight (Da)	18,967
Isoelectric Point (pI)	10.08

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Nce102p (InterPro)
Transmembrane Domains	There are 4 total predicted transmembrane domains (TMHMM)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 13 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012FE36 \| Q12207 MIPS: YPR149W NCBI: 1066478 \| 1197842 \| 1508863 \| 2498617 \| 45270936 \| 6325407 \| NP_015475.1 GenBank/EMBL/DDBJ: DAA11562.1 \| AY558523 \| U40829 \| U41659 \| U65683

Amino Acid Sequence (or in FASTA format)
1 MLALADNILR IINFLFLVIS IGLISSLLNT QHRHSSRVNY CMFACAYGIF 51 TDSLYGVFAN FIEPLAWPLV LFTLDFLNFV FTFTAGTVLA VGIRAHSCNN 101 SSYVDSNKIT QGSGTRCRQA QAAVAFLYFS CAIFLAKTLM SVFNMISNGA 151 FGSGSFSKRR RTGQVGVPTI SQV*

Amino Acid Sequence (or in FASTA format)

       1  MLALADNILR IINFLFLVIS IGLISSLLNT QHRHSSRVNY CMFACAYGIF
      51  TDSLYGVFAN FIEPLAWPLV LFTLDFLNFV FTFTAGTVLA VGIRAHSCNN
     101  SSYVDSNKIT QGSGTRCRQA QAAVAFLYFS CAIFLAKTLM SVFNMISNGA
     151  FGSGSFSKRR RTGQVGVPTI SQV*

external links for Nce102p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
Candida (CandidaDB)	Complexome
YGOB	DIP
YOGY	GeneMANIA
	YeastRC Mass Spec (Seattle)
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Nce102p

1)	Cleves AE, et al. (1996) A new pathway for protein export in Saccharomyces cerevisiae. J Cell Biol 133(5):1017-26
2)	Bagnat M, et al. (2000) Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast. Proc Natl Acad Sci U S A 97(7):3254-9
3)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61