SRP54/YPR088C Protein Information

Standard Name	Srp54p
Systematic Name	Ypr088cp
Alias	Srh1p
ORF Classification	Verified
Description	Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains the signal sequence-binding activity of SRP, interacts with the SRP RNA, and mediates binding of SRP to signal receptor; contains GTPase domain (1)
Name Description	Signal Recognition Particle

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	541
Molecular Weight (Da)	59,624
Isoelectric Point (pI)	9.04

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Srp54p (InterPro)
Physical Interactions	There are 44 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000052E7E \| P20424 MIPS: YPR088C NCBI: 1230693 \| 1711516 \| 172705 \| 4538 \| 4542 \| 6325345 \| NP_015413.1 GenBank/EMBL/DDBJ: DAA11505.1 \| M55517 \| U51033 \| X16908 \| X51614

Amino Acid Sequence (or in FASTA format)
1 MVLADLGKRI NSAVNNAISN TQDDFTTSVD VMLKGIVTAL LESDVNIALV 51 SKLRNNIRSQ LLSENRSEKS TTNAQTKKLI QKTVFDELCK LVTCEGSEEK 101 AFVPKKRKTN IIMFVGLQGS GKTTSCTKLA VYYSKRGFKV GLVCADTFRA 151 GAFDQLKQNA IRARIPFYGS YTETDPAKVA EEGINKFKKE KFDIIIVDTS 201 GRHHQEEELF QEMIEISNVI KPNQTIMVLD ASIGQAAEQQ SKAFKESSDF 251 GAIILTKMDG HARGGGAISA VAATNTPIIF IGTGEHIHDL EKFSPKSFIS 301 KLLGIGDIES LFEQLQTVSN KEDAKATMEN IQKGKFTLLD FKKQMQTIMK 351 MGPLSNIAQM IPGMSNMMNQ VGEEETSQKM KKMVYVLDSM TKEELESDGR 401 MFIEEPTRMV RVAKGSGTSV FEVEMILMQQ QMMARMAQTA TQQQPGAPGA 451 NARMPGMPNM PGMPNMPGMP NMPGMPKVTP QMMQQAQQKL KQNPGLMQNM 501 MNMFGGGMGG GMGGGMPDMN EMMKMMQDPQ MQQMAKQFGM G*

Amino Acid Sequence (or in FASTA format)

       1  MVLADLGKRI NSAVNNAISN TQDDFTTSVD VMLKGIVTAL LESDVNIALV
      51  SKLRNNIRSQ LLSENRSEKS TTNAQTKKLI QKTVFDELCK LVTCEGSEEK
     101  AFVPKKRKTN IIMFVGLQGS GKTTSCTKLA VYYSKRGFKV GLVCADTFRA
     151  GAFDQLKQNA IRARIPFYGS YTETDPAKVA EEGINKFKKE KFDIIIVDTS
     201  GRHHQEEELF QEMIEISNVI KPNQTIMVLD ASIGQAAEQQ SKAFKESSDF
     251  GAIILTKMDG HARGGGAISA VAATNTPIIF IGTGEHIHDL EKFSPKSFIS
     301  KLLGIGDIES LFEQLQTVSN KEDAKATMEN IQKGKFTLLD FKKQMQTIMK
     351  MGPLSNIAQM IPGMSNMMNQ VGEEETSQKM KKMVYVLDSM TKEELESDGR
     401  MFIEEPTRMV RVAKGSGTSV FEVEMILMQQ QMMARMAQTA TQQQPGAPGA
     451  NARMPGMPNM PGMPNMPGMP NMPGMPKVTP QMMQQAQQKL KQNPGLMQNM
     501  MNMFGGGMGG GMGGGMPDMN EMMKMMQDPQ MQQMAKQFGM G*

external links for Srp54p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Srp54p

1)	Ogg SC, et al. (1998) A functional GTPase domain, but not its transmembrane domain, is required for function of the SRP receptor beta-subunit. J Cell Biol 142(2):341-54