ASA1/YPR085C Protein Information

Standard Name	Asa1p 1
Systematic Name	Ypr085cp
ORF Classification	Verified
Description	Subunit of the ASTRA complex, involved in chromatin remodeling; telomere length regulator involved in the stability or biogenesis of PIKKs such as TORC1 (1, 2, 3)
Name Description	AStra Associated protein 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	443
Molecular Weight (Da)	50,563
Isoelectric Point (pI)	7.44

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Asa1p (InterPro)
Physical Interactions	There are 3 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001D47AF \| Q06822 MIPS: YPR085C NCBI: 115502929 \| 1230691 \| 37362704 \| NP_015410.2 GenBank/EMBL/DDBJ: DAA11503.1 \| U51033

Amino Acid Sequence (or in FASTA format)
1 MRGFSNEIIL KRTLTLSDFT LRYHKRGITA LQVIKAPSVS NVPVLLSGDN 51 YGYFVMWDLV TKRPITHIEI EGNSHIIAFW WVETTNVLYI LSKDSMLRIF 101 ELDSSTQLSI DLVRKLSQAN KTDHLQWTKI YEMPINTLNF ANFIIEAEVK 151 PTKDNKSYRL VCCHTDDSET IDIYQIIEDS TFKLKRPFNN INFPRFLKQQ 201 NFLGISKDSK FGIIMRFAKL NDVIFLGYEN GFVVGFKITF DEGLQRDIAE 251 LVHVSNDHYP NPILDMCVSG DELYSCSTDD FITKYKIPVN LQLETKYLRD 301 DALLIKCPSS LRVSEPSKVH LPLKNIGHID KVKDDYLVVS SWSGMTIVYN 351 MRTSEVEQTF VKSKNNLVVS DSSMGDLTNG SGSNTESSSK SHNYKVGAMT 401 CLESFDVQSD GLRLGQLRRI KALAKCNWCL IGYEDGTIKL NKI*

Amino Acid Sequence (or in FASTA format)

       1  MRGFSNEIIL KRTLTLSDFT LRYHKRGITA LQVIKAPSVS NVPVLLSGDN
      51  YGYFVMWDLV TKRPITHIEI EGNSHIIAFW WVETTNVLYI LSKDSMLRIF
     101  ELDSSTQLSI DLVRKLSQAN KTDHLQWTKI YEMPINTLNF ANFIIEAEVK
     151  PTKDNKSYRL VCCHTDDSET IDIYQIIEDS TFKLKRPFNN INFPRFLKQQ
     201  NFLGISKDSK FGIIMRFAKL NDVIFLGYEN GFVVGFKITF DEGLQRDIAE
     251  LVHVSNDHYP NPILDMCVSG DELYSCSTDD FITKYKIPVN LQLETKYLRD
     301  DALLIKCPSS LRVSEPSKVH LPLKNIGHID KVKDDYLVVS SWSGMTIVYN
     351  MRTSEVEQTF VKSKNNLVVS DSSMGDLTNG SGSNTESSSK SHNYKVGAMT
     401  CLESFDVQSD GLRLGQLRRI KALAKCNWCL IGYEDGTIKL NKI*

external links for Asa1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Asa1p

1)	Shevchenko A, et al. (2008) Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Genome Biol 9(11):R167
2)	Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
3)	Stirling PC, et al. (2011) The Complete Spectrum of Yeast Chromosome Instability Genes Identifies Candidate CIN Cancer Genes and Functional Roles for ASTRA Complex Components. PLoS Genet 7(4):e1002057