YPL260W Protein Information Help

Systematic Name Ypl260wp
ORF Classification Verified
Description Putative substrate of cAMP-dependent protein kinase (PKA); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YPL260W is not an essential gene; protein abundance increases in response to DNA replication stress (1, 2, 3)
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 551
Molecular Weight (Da) 62,779
Isoelectric Point (pI) 4.85

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ypl260wp (InterPro)
Physical Interactions There are 6 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000006B65F | Q08977
MIPS: YPL260W
NCBI: 1370539 | 2326846 | 6324994 | 74583782 | 808836 | NP_015063.1
GenBank/EMBL/DDBJ: DAA11175.1 | J02802 | Z73615 | Z73617
Amino Acid Sequence (or in FASTA format)
 
       1  MFASAGQQHP QIVPKEEESI LNYLLEVRSS LAKLKQNRTQ YLNSKDVQTT
      51  YQHVLTKVRE LDDIRKNSHE TPAKSAATLI HSTELHNRVD SVLDDVFQLL
     101  SLCFLTVGLK NSAPATYASL STVESLLEHL NESNVFTHHD LSPIKERLEE
     151  ISKIVEQKNS SPAYDEDGND DRLREIDNER KKNKIEEDLL LRAKLKHCKD
     201  EYDILEGKLE EIDPSLSTVM EKLFRIRRGL LSLVASAKKT MSKSDINTNS
     251  LLQEQNDLQT NNESLTDDKH LVSQEYVHEK LSVLKNELSE LESNRDDSGK
     301  FKSLESHQVA EKGQSVLNGL LDDCHDLVND LSHQKNGGLT LDPYLQPIYE
     351  QLIDIKTTLE NLMITRRWTL RETDLFSYQK KLNEIDNKRI NGKFPTKSQD
     401  SKGQSILLYL LRRCYAIIYK LLESSEPVSE ALQPIHNQLS TVRRCLLELK
     451  RMGGVNNERE LYPYQMKLAS LDNLRTEGIF YDSDGNIPEG QGILNALLAE
     501  CFDILHELKV EAEEKAQNST SSDGSDDDDN GESGIDSNSN DSEPESEYQQ
     551  E*

external links for Ypl260wp
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Aspergillus (AspGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CGD) CYC2008 (complexes) Pfam domains
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Ypl260wp
1) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
2) Budovskaya YV, et al.  (2005) An evolutionary proteomics approach identifies substrates of the cAMP-dependent protein kinase. Proc Natl Acad Sci U S A 102(39):13933-8
3) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76