YPL247C Protein Information

Systematic Name	Ypl247cp
ORF Classification	Uncharacterized
Description	Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; similar to the petunia WD repeat protein an11; overexpression causes a cell cycle delay or arrest (1, 2, 3, 4)

Experimental Data
Molecules/cell	799 5

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	523
Molecular Weight (Da)	57,323
Isoelectric Point (pI)	5.8

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ypl247cp (InterPro)
Physical Interactions	There are 5 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000006BDA0 \| Q12523 MIPS: YPL247C NCBI: 1061242 \| 1370509 \| 6325009 \| 74676619 \| NP_015077.1 GenBank/EMBL/DDBJ: DAA11190.1 \| Z67751 \| Z73603

Amino Acid Sequence (or in FASTA format)
1 MDPFHNGNKR SSISFGSSQR QPYNKNNYLS GTNGPSSAAQ DQGRGPSPFG 51 MSGNTTNGGN SKRNSGCDLS ATYYASRSPM YSPLDFSPPV FSPNHSQLQQ 101 ARGYAANIPV VSNLMNPSMA SVCEYQSHYP LFGLDWSADD YVCLGSYKED 151 SRNKLQVLHS NDLLSWESVV DADVVYPVSK IQWVPSQLYP RKLATCSDSL 201 RIWSVSPEER QFQEQINLSL CKYNRQHPAN PAAADDMKVI GTFPPITSFD 251 WNTVDTNLII SSSIDTTCIV WDLQSSHYVK TQLIAHDSEV FDVRFLTKST 301 QLFASCGGDG SVRVFDLRSL AHSTIIYEPP SSSVSGATAG TITPSSKGSD 351 ALLRLEPSPY DPNVLATFAA DSNKIIILDM RNPESPILNL QGHGSSVNGI 401 KWHPTKRNVL LSCGDDCQVL YWDLNSSFME INAAGSKSPS IHGTSLEDPD 451 GDTEMTDGGA GSGLNEDPLS LNNNSKQVCK TLETPNMMYA NKTQEINNIA 501 WRPQRGDWFG CVSGKKFQNV RVL*

Amino Acid Sequence (or in FASTA format)

       1  MDPFHNGNKR SSISFGSSQR QPYNKNNYLS GTNGPSSAAQ DQGRGPSPFG
      51  MSGNTTNGGN SKRNSGCDLS ATYYASRSPM YSPLDFSPPV FSPNHSQLQQ
     101  ARGYAANIPV VSNLMNPSMA SVCEYQSHYP LFGLDWSADD YVCLGSYKED
     151  SRNKLQVLHS NDLLSWESVV DADVVYPVSK IQWVPSQLYP RKLATCSDSL
     201  RIWSVSPEER QFQEQINLSL CKYNRQHPAN PAAADDMKVI GTFPPITSFD
     251  WNTVDTNLII SSSIDTTCIV WDLQSSHYVK TQLIAHDSEV FDVRFLTKST
     301  QLFASCGGDG SVRVFDLRSL AHSTIIYEPP SSSVSGATAG TITPSSKGSD
     351  ALLRLEPSPY DPNVLATFAA DSNKIIILDM RNPESPILNL QGHGSSVNGI
     401  KWHPTKRNVL LSCGDDCQVL YWDLNSSFME INAAGSKSPS IHGTSLEDPD
     451  GDTEMTDGGA GSGLNEDPLS LNNNSKQVCK TLETPNMMYA NKTQEINNIA
     501  WRPQRGDWFG CVSGKKFQNV RVL*

external links for Ypl247cp

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Ypl247cp

1)	de Vetten N, et al. (1997) The an11 locus controlling flower pigmentation in petunia encodes a novel WD-repeat protein conserved in yeast, plants, and animals. Genes Dev 11(11):1422-34
2)	Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
3)	Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
4)	Niu W, et al. (2008) Mechanisms of Cell Cycle Control Revealed by a Systematic and Quantitative Overexpression Screen in S. cerevisiae. PLoS Genet 4(7):e1000120
5)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41