USV1/YPL230W Protein Information

Standard Name	Usv1p 1, 2
Systematic Name	Ypl230wp
Alias	Nsf1p 3
ORF Classification	Verified
Description	Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in growth on non-fermentable carbon sources, response to salt stress and cell wall biosynthesis; USV1 has a paralog, RGM1, that arose from the whole genome duplication (3, 4, 5, 6, 7)
Name Description	Up in StarVation

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	391
Molecular Weight (Da)	43,517
Isoelectric Point (pI)	10.59

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Usv1p (InterPro)
Physical Interactions	There are 2 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000006BA16 \| Q12132 MIPS: YPL230W NCBI: 1181258 \| 1370476 \| 6325026 \| 74676532 \| NP_015094.1 GenBank/EMBL/DDBJ: DAA11206.1 \| X94561 \| Z73586

Amino Acid Sequence (or in FASTA format)
1 MENTTNRNTA GVLTSSNGNF ATNSVAASTP KRSKSARRKT FKCTGYDGCT 51 MSFTRAEHLA RHIRKHTGEK PFQCPACLKF FSRVDNLKQH RESVHAHKNH 101 HSTSSHQRKP SSSSLSSSSS ASSSSSASSS TSYSDPYRKT NINSGNMPMM 151 AENEKAPQII HSSPEFITST RSIPPISPRS IYNTQRQQQH QQQQHQQAPY 201 YFPSHPITDS YYQYPLPSNN NTINYLPSVD VQYPLNVSPS STSHPASEVI 251 ISSFPPRSMP STSFKYKDSA DFQARTTMNK YNIRPSNINV NTSNINNHLD 301 SFSPPFSPST TVAEAKPIIL PQYQQAFSQP PNGNKNNNMS SSKNGGKGGE 351 NFKNTDDRND NNNKKRSETL SESDISVNTN KKRLSVDYIL T*

Amino Acid Sequence (or in FASTA format)

       1  MENTTNRNTA GVLTSSNGNF ATNSVAASTP KRSKSARRKT FKCTGYDGCT
      51  MSFTRAEHLA RHIRKHTGEK PFQCPACLKF FSRVDNLKQH RESVHAHKNH
     101  HSTSSHQRKP SSSSLSSSSS ASSSSSASSS TSYSDPYRKT NINSGNMPMM
     151  AENEKAPQII HSSPEFITST RSIPPISPRS IYNTQRQQQH QQQQHQQAPY
     201  YFPSHPITDS YYQYPLPSNN NTINYLPSVD VQYPLNVSPS STSHPASEVI
     251  ISSFPPRSMP STSFKYKDSA DFQARTTMNK YNIRPSNINV NTSNINNHLD
     301  SFSPPFSPST TVAEAKPIIL PQYQQAFSQP PNGNKNNNMS SSKNGGKGGE
     351  NFKNTDDRND NNNKKRSETL SESDISVNTN KKRLSVDYIL T*

external links for Usv1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
YGOB	BioPIXIE	MIPS	YeastGFP
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	GeneMANIA

References cited on this page View Complete Literature Guide for Usv1p

1)	Marchfelder U, et al. (2003) SIR-dependent repression of non-telomeric genes in Saccharomyces cerevisiae? Yeast 20(9):797-801
2)	McCammon MT, et al. (2003) Global transcription analysis of Krebs tricarboxylic acid cycle mutants reveals an alternating pattern of gene expression and effects on hypoxic and oxidative genes. Mol Biol Cell 14(3):958-72
3)	Hlynialuk C, et al. (2008) Nsf1/Ypl230w participates in transcriptional activation during non-fermentative growth and in response to salt stress in Saccharomyces cerevisiae. Microbiology 154(Pt 8):2482-91
4)	Bohm S, et al. (1997) Variations of the C2H2 zinc finger motif in the yeast genome and classification of yeast zinc finger proteins. Nucleic Acids Res 25(12):2464-9
5)	Segal E, et al. (2003) Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data. Nat Genet 34(2):166-76
6)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
7)	Middendorf M, et al. (2004) Predicting genetic regulatory response using classification. Bioinformatics 20 Suppl 1():i232-40