SVS1/YPL163C Protein Information

Standard Name	Svs1p
Systematic Name	Ypl163cp
ORF Classification	Verified
Description	Cell wall and vacuolar protein; required for wild-type resistance to vanadate; SVS1 has a paralog, SRL1, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description	Suppressor of Vanadate Sensitivity 1

Experimental Data
Molecules/cell	688 5

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	260
Molecular Weight (Da)	27,611
Isoelectric Point (pI)	3.95

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Svs1p (InterPro)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 2 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000136297 \| Q12254 MIPS: YPL163C NCBI: 1370346 \| 1403546 \| 2498978 \| 45270162 \| 6325094 \| 780164 \| NP_015162.1 GenBank/EMBL/DDBJ: DAA11271.1 \| AY558136 \| D50278 \| X96770 \| Z73519

Amino Acid Sequence (or in FASTA format)
1 MIFKILCSLL LVTSNFASAL YVNETTSYTP YTKTLTPTYS VSPQETTLTY 51 SDETTTFYIT STFYSTYWFT TSQSAAIIST PTASTPTAST PSLTTSTNEY 101 TTTYSDTDTT YTSTLTSTYI ITLSTESANE KAEQISTSVT EIASTVTESG 151 STYTSTLTST LLVTVYNSQA SNTIATSTAG DAASNVDALE KLVSAEHQSQ 201 MIQTTSADEQ YCSASTKYVT VTAAAVTEVV TTTAEPVVKY VTITADASNV 251 TGSANNGTHI *

Amino Acid Sequence (or in FASTA format)

       1  MIFKILCSLL LVTSNFASAL YVNETTSYTP YTKTLTPTYS VSPQETTLTY
      51  SDETTTFYIT STFYSTYWFT TSQSAAIIST PTASTPTAST PSLTTSTNEY
     101  TTTYSDTDTT YTSTLTSTYI ITLSTESANE KAEQISTSVT EIASTVTESG
     151  STYTSTLTST LLVTVYNSQA SNTIATSTAG DAASNVDALE KLVSAEHQSQ
     201  MIQTTSADEQ YCSASTKYVT VTAAAVTEVV TTTAEPVVKY VTITADASNV
     251  TGSANNGTHI *

external links for Svs1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
YGOB	BioPIXIE	MIPS	YeastGFP
YOGY	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
	Complexome
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Svs1p

1)	Nakamura T, et al. (1995) Cloning and characterization of the Saccharomyces cerevisiae SVS1 gene which encodes a serine- and threonine-rich protein required for vanadate resistance. Gene 165(1):25-9
2)	Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
3)	Terashima H, et al. (2002) Sequence-based approach for identification of cell wall proteins in Saccharomyces cerevisiae. Curr Genet 40(5):311-6
4)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41