NOG1/YPL093W Protein Information Help

Standard Name Nog1p 1
Systematic Name Ypl093wp
ORF Classification Verified
Description Putative GTPase; associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins (1, 2, 3)
Name Description NucleOlar G-protein 1
Experimental Data
Molecules/cell 28000 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 647
Molecular Weight (Da) 74,409
Isoelectric Point (pI) 9.38

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Nog1p (InterPro)
Physical Interactions There are 333 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000052E39 | Q02892
MIPS: YPL093W
NCBI: 1151233 | 17368412 | 6325164 | NP_015232.1 | NM_001183907.1
GenBank/EMBL/DDBJ: AAB68206.1 | DAA11340.1 | U43281
Amino Acid Sequence (or in FASTA format)
       1  MQLSWKDIPT VAPANDLLDI VLNRTQRKTP TVIRPGFKIT RIRAFYMRKV
      51  KYTGEGFVEK FEDILKGFPN INDVHPFHRD LMDTLYEKNH YKISLAAISR
     101  AKSLVEQVAR DYVRLLKFGQ SLFQCKQLKR AALGRMATIV KKLRDPLAYL
     151  EQVRQHIGRL PSIDPNTRTL LICGYPNVGK SSFLRCITKS DVDVQPYAFT
     201  TKSLYVGHFD YKYLRFQAID TPGILDRPTE EMNNIEMQSI YAIAHLRSCV
     251  LYFMDLSEQC GFTIEAQVKL FHSIKPLFAN KSVMVVINKT DIIRPEDLDE
     301  ERAQLLESVK EVPGVEIMTS SCQLEENVME VRNKACEKLL ASRIENKLKS
     351  QSRINNVLNK IHVAQPQARD DVKRTPFIPE SVKNLKKYDP EDPNRRKLAR
     401  DIEAENGGAG VFNVNLKDKY LLEDDEWKND IMPEILDGKN VYDFLDPEIA
     451  AKLQALEEEE EKLENEGFYN SDDEEEIYDG FEASEVDDIK EKAAWIRNRQ
     501  KTMIAEARNR KSLKNKAIMP RSKLTKSFGK MEEHMSTLGH DMSALQDKQN
     551  RAARKNRYVE RGSDVVFGDQ DALTASTENG VKLRQTDRLL DGVADGSMRS
     601  KADRMAKMER RERNRHAKQG ESDRHNAVSL SKHLFSGKRG VGKTDFR*  

external links for Nog1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) CYC2008 (complexes) MIPS YeastGFP
Candida (CGD) Complexome Pfam domains YeastRC Public Image Repository
YGOB DIP YeastRC Structure Prediction (Seattle)
YOGY GeneMANIA


IMP


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Nog1p
1) Park JH, et al.  (2001) A novel nucleolar G-protein conserved in eukaryotes. J Cell Sci 114(Pt 1):173-185
2) Kallstrom G, et al.  (2003) The putative GTPases Nog1p and Lsg1p are required for 60S ribosomal subunit biogenesis and are localized to the nucleus and cytoplasm, respectively. Mol Cell Biol 23(12):4344-55
3) Horsey EW, et al.  (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41