YTA6/YPL074W Protein Information Help

Standard Name Yta6p 1
Systematic Name Ypl074wp
ORF Classification Verified
Description Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family; localized to the cortex of mother cells but not to daughter cells; relocalizes from cytoplasm to plasma membrane foci upon DNA replication stress (1, 2, 3, 4)
Name Description Yeast Tat-binding Analog 1
Experimental Data
Molecules/cell 259 5
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 754
Molecular Weight (Da) 85,299
Isoelectric Point (pI) 10.45

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Yta6p (InterPro)
Physical Interactions There are 44 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000136A7D | P40328
MIPS: YPL074W
NCBI: 1147619 | 19859302 | 531761 | 531762 | 6325183 | 808837 | NP_015251.1
GenBank/EMBL/DDBJ: DAA11358.1 | M14145 | U41849 | X81071
Amino Acid Sequence (or in FASTA format)
       1  MAHEKFSIPE NFTLAQSLQL LYSVVKNQYK NLADLIINSK GNKDTVTYGK
      51  IHKNLDTLLV YVNEGLRKIE KTYTLKKGLG NLVVDHPELR SIIEDFQILG
     101  QDIRIARRKA ETLMAEGNGS PSLSSSSSVL GLGTGNGLRF PKLWRMGSKR
     151  DKLKEADEKE AKINKQADNI RRARKLEEEK KLGAKLQYER DLELQREKLI
     201  ELKVKEKVEF EVAQKLEEER VKREEEERKH REQAEKKRIS TLKHERKTNY
     251  KSRASLDNFS SSSKSSGKID NSLIKRRSLD VVRTSGERVR TPVRKSMEAA
     301  EIGMAAQLAW SQYQNGANHS KVSNNGSHSN ELQIRYKPTP PLKKRYDYKK
     351  PTVNRPIIKS PTLNRQNSKS SRNIPTNSKL KASKSNTNKV SRRNEQNLEP
     401  SSPVLVSATA VPAESKPMRS KSGTPDKESS ASSSLDSRKE DILKSVQGVD
     451  RNACEQILNE ILVTDEKVYW EDIAGLRNAK NSLKEAVVYP FLRPDLFKGL
     501  REPVRGMLLF GPPGTGKTMI AKAVATESNS TFFSVSASSL LSKYLGESEK
     551  LVRALFYMAK KLSPSIIFID EIDSMLTARS DNENESSRRI KTELLIQWSS
     601  LSSATAQSED RNNTLDSRVL VLGATNLPWA IDDAARRRFS RKLYIPLPDY
     651  ETRLYHLKRL MAKQKNSLQD LDYELITEMT EGFSGSDLTS LAKEAAMEPI
     701  RDLGDKLMFA DFDKIRGIEI KDFQNALLTI KKSVSSESLQ KYEEWSSKFG
     751  SNGS*                                                 

external links for Yta6p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
YGOB BioPIXIE MIPS YeastGFP
YOGY CYC2008 (complexes) Pfam domains YeastRC Public Image Repository

Complexome YeastRC Structure Prediction (Seattle)

DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Yta6p
1) Schnall R, et al.  (1994) Identification of a set of yeast genes coding for a novel family of putative ATPases with high similarity to constituents of the 26S protease complex. Yeast 10(9):1141-55
2) Swaffield JC and Purugganan MD  (1997) The evolution of the conserved ATPase domain (CAD): reconstructing the history of an ancient protein module. J Mol Evol 45(5):549-63
3) Beach DL and Bloom K  (2001) ASH1 mRNA localization in three acts. Mol Biol Cell 12(9):2567-77
4) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
5) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41