SRL4/YPL033C Protein Information Help

Standard Name Srl4p 1
Systematic Name Ypl033cp
ORF Classification Verified
Description Protein of unknown function; involved in regulation of dNTP production; null mutant suppresses the lethality of lcd1 and rad53 mutations; expression is induced by Kar4p (1, 2, 3)
Name Description Suppressor of Rad53 null Lethality or Suppressor of Rad53 and Lcd1 1
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 281
Molecular Weight (Da) 31,925
Isoelectric Point (pI) 7.41

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Srl4p (InterPro)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000006B054 | Q03085
MIPS: YPL033C
NCBI: 1171424 | 6325224 | 74676340 | NP_015292.1
GenBank/EMBL/DDBJ: DAA11396.1 | U44030
Amino Acid Sequence (or in FASTA format)
 
       1  MKKTIYKVLV SFYQYVGLGK KFHPSHDTVL IIGGSSNELG IELCETFIED
      51  YHTKVINIDT IDSINGKNAR RSEKLYTFIS CKDFSDIKCL EESMLYLQNL
     101  EIIPTVLINN MQEGIESTLL KEDKFLRLDE ESLNEFEKIV RYNLQSVILI
     151  TKFCLSNIFP KVQAEAQEKA KGFYIVNISS VLTLKPCKSG THFITSKCGI
     201  NSFHDGITSE LKLKDSNLNV KTLIAYLPSF ESEAHWKRLS PSISKHLVHC
     251  LLEGRYGDTI LESKRSIGDI LLITGFKSSF T*

external links for Srl4p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS
YOGY CYC2008 (complexes) Pfam domains

Complexome YeastRC Structure Prediction (Seattle)

GeneMANIA

References cited on this page View Complete Literature Guide for Srl4p
1) Choi DH, et al.  (2008) The Mutation of a Novel Saccharomyces cerevisiae SRL4 Gene Rescues the Lethality of rad53 and lcd1 Mutations by Modulating dNTP Levels. J Microbiol 46(1):75-80
2) Perkins EL, et al.  (1999) Yeast and human genes that affect the Escherichia coli SOS response. Proc Natl Acad Sci U S A 96(5):2204-9
3) Lahav R, et al.  (2007) Role of transcription factor Kar4 in regulating downstream events in the Saccharomyces cerevisiae pheromone response pathway. Mol Cell Biol 27(3):818-29