SUV3/YPL029W Protein Information Help

Standard Name Suv3p 1
Systematic Name Ypl029wp
Alias Lpb2p
ORF Classification Verified
Description ATP-dependent RNA helicase, component of the mitochondrial degradosome along with the RNase Dss1p; the degradosome associates with the ribosome and mediates RNA turnover; also required during splicing of the COX1 AI5_beta intron (2, 3)
Name Description SUppressor of Var1 1
Experimental Data
Molecules/cell 1440 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 737
Molecular Weight (Da) 84,324
Isoelectric Point (pI) 9.74

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Suv3p (InterPro)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 4 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013628A | P32580
MIPS: YPL029W
NCBI: 1039448 | 172798 | 2506501 | 6325228 | NP_015296.1
GenBank/EMBL/DDBJ: DAA11400.1 | M91167 | U36624
External Classifications EC: 3.6.1.- [Hydrolases acting on acid anhydrides in phosphorous-containing anhydrides]
EC: 3.6.4.13 [RNA helicase]
Amino Acid Sequence (or in FASTA format)
 
       1  MALVKYSTVF FPLRSLRLFV SIKKAYYHSE PHSIDLFHDK DWIVKRPKFL
      51  NLPKNEHSKL DIFQFNFNKS ESNNVYLQDS SFKDNLDKAM QFIYNDKLSS
     101  LDAKQVPIKN LAWLKLRDYI YQQLKDPKLQ AKTYVPSVSE IIHPSSPGNL
     151  ISLLINCNKI SNLVWKSVLK YSLSNNITTL DKFIHVLQQT FDHVYEQEIL
     201  PMMTNTDDTD GAHNVDITNP AEWFPEARKI RRHIIMHIGP TNSGKTYRAL
     251  QKLKSVDRGY YAGPLRLLAR EVYDRFHAEK IRCNLLTGEE VIRDLDDRGN
     301  SAGLTSGTVE MVPINQKFDV VVLDEIQMMS DGDRGWAWTN ALLGVVSKEV
     351  HLCGEKSVLP LVKSIVKMTG DKLTINEYER LGKLSVEEKP IKDGIKGLRK
     401  GDCVVAFSKK KILDLKLKIE KDTNLKVAVI YGSLPPETRV QQAALFNNGE
     451  YDIMVASDAI GMGLNLSIDR VVFTTNMKYN GEELMEMTSS QIKQIGGRAG
     501  RFKSRSASGG VPQGFITSFE SKVLKSVRKA IEAPVEYLKT AVTWPTDEIC
     551  AQLMTQFPPG TPTSVLLQTI SDELEKSSDN LFTLSDLKSK LKVIGLFEHM
     601  EDIPFFDKLK LSNAPVKDMP MVTKAFTKFC ETIAKRHTRG LLSYRLPFNL
     651  LDYNCIPNES YSLEVYESLY NIITLYFWLS NRYPNYFIDM ESAKDLKYFC
     701  EMIIFEKLDR LKKNPYAHKP FGSTRGHLSS SRRRLRT*

external links for Suv3p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Aspergillus (AspGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CGD) CYC2008 (complexes) Pfam domains
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Suv3p
1) Butow RA, et al.  (1989) The role of a conserved dodecamer sequence in yeast mitochondrial gene expression. Genome 31(2):757-60
2) Dziembowski A, et al.  (2003) The yeast mitochondrial degradosome. Its composition, interplay between RNA helicase and RNase activities and the role in mitochondrial RNA metabolism. J Biol Chem 278(3):1603-11
3) Turk EM and Caprara MG  (2010) Splicing of Yeast aI5{beta} Group I Intron Requires SUV3 to Recycle MRS1 via Mitochondrial Degradosome-promoted Decay of Excised Intron Ribonucleoprotein (RNP). J Biol Chem 285(12):8585-94
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41