ULA1/YPL003W Protein Information

Standard Name	Ula1p
Systematic Name	Ypl003wp
Alias	Enr2p 1
ORF Classification	Verified
Description	Protein that acts together with Uba3p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation (2)
Name Description	Ubiquitin-Like protein Activation 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	462
Molecular Weight (Da)	52,852
Isoelectric Point (pI)	5.07

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ula1p (InterPro)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 13 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000006A580 \| Q12059 MIPS: YPL003W NCBI: 1314073 \| 2980751 \| 46396761 \| 6325254 \| 683787 \| 965090 \| NP_015322.1 GenBank/EMBL/DDBJ: DAA11425.1 \| U33335 \| Y16889 \| Z48483 \| Z71255

Amino Acid Sequence (or in FASTA format)
1 MERYDRQLRL WGALGQDSLN RSRVCVVGPA TPLLQEVFKN LVLAGISSLT 51 WLKVECAVQS GSLFLAELKK DLEPLASKQL EYEENDLRKT LQQPQYDWTR 101 FSVVILTCIG EQTAMLDLNE IRRQRGTKFP PVLNTFVSGF YGYIYLVLSE 151 THFVLQAHPD SKKYDLRLQN PWPELINYVD TFDLSKMDTA TFSGIPYTVL 201 LMKCIAKLER DGNNGRITID QMKKVLDQIC LPLGNDVIYE PNYVEAKRYA 251 YLACSQNDCC KELEDLLRNL EISDYGNDWH DTYNYEILTL LLTLKNIAKE 301 NGELSFQPLT GTLPDMESTT ENYIRLKKLY EVKAKLDKSR VEESLARSKK 351 IVSQDVLETF CSHYGEVRKI LPPKSDLLGI FSTSNALLDA LVMVQFWEQP 401 AVTAEDKDEF IGLRVDDNYS VMAFFGGAVV QEAIKLITHH YVPIDNLFLY 451 NGINNSSATY KI*

Amino Acid Sequence (or in FASTA format)

       1  MERYDRQLRL WGALGQDSLN RSRVCVVGPA TPLLQEVFKN LVLAGISSLT
      51  WLKVECAVQS GSLFLAELKK DLEPLASKQL EYEENDLRKT LQQPQYDWTR
     101  FSVVILTCIG EQTAMLDLNE IRRQRGTKFP PVLNTFVSGF YGYIYLVLSE
     151  THFVLQAHPD SKKYDLRLQN PWPELINYVD TFDLSKMDTA TFSGIPYTVL
     201  LMKCIAKLER DGNNGRITID QMKKVLDQIC LPLGNDVIYE PNYVEAKRYA
     251  YLACSQNDCC KELEDLLRNL EISDYGNDWH DTYNYEILTL LLTLKNIAKE
     301  NGELSFQPLT GTLPDMESTT ENYIRLKKLY EVKAKLDKSR VEESLARSKK
     351  IVSQDVLETF CSHYGEVRKI LPPKSDLLGI FSTSNALLDA LVMVQFWEQP
     401  AVTAEDKDEF IGLRVDDNYS VMAFFGGAVV QEAIKLITHH YVPIDNLFLY
     451  NGINNSSATY KI*

external links for Ula1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS
YGOB	CYC2008 (complexes)	Pfam domains
YOGY	Complexome
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Ula1p

1)	Lammer D, et al. (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12(7):914-26
2)	Liakopoulos D, et al. (1998) A novel protein modification pathway related to the ubiquitin system. EMBO J 17(8):2208-14