RDR1/YOR380W Protein Information

Standard Name	Rdr1p
Systematic Name	Yor380wp
ORF Classification	Verified
Description	Transcriptional repressor involved in the control of multidrug resistance; negatively regulates expression of the PDR5 gene; member of the Gal4p family of zinc cluster proteins (1)
Name Description	Repressor of Drug Resistance 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	546
Molecular Weight (Da)	61,287
Isoelectric Point (pI)	7.77

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rdr1p (InterPro)
Physical Interactions	There are 13 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000006A54E \| Q08904 MIPS: YOR380W NCBI: 1420819 \| 398366433 \| 74655024 \| NP_015025.3 \| NM_001183800.3 GenBank/EMBL/DDBJ: DAA11138.1 \| Z75288

Amino Acid Sequence (or in FASTA format)
1 MASPGSTALP HKRQRVRKAC VPCRERKRKC NGKSPCEMCV AYGYVCHYID 51 GRVPSASPQV QQVGETSPDT ESRPFVLPGI HRNEQPQPIN TQNVTSQNIV 101 DPTKSRYTIQ HSAVAFPRCL GLELRSTNPP RLHSFAWHCG IRPEENPNSH 151 VLLSDLVTKE EYYRISKVYF SVVHPIFDVV NPEQLAKNVE KYWDGDVKTL 201 EYGAVIAGVI ALGSFFMGSL GHPREMDIVQ YAKGILDDPT FSRIPTVEQV 251 SAWVLRTIYL RATSRPHVAW LASCVTIHLS EAIGLHHEID REDIAISNNV 301 PPKRTTVVSE HTRRLFWCAW SINTILSYDY GRSSVTLNRI TCKPVKETDG 351 NFTAHLVALA HLIPQDSVNA NAAQLLQALA AVHESPNAHP FLSLTKGDIC 401 LSLYRRLRLL NHILDKNVVL QIIDIGNTAL SAAYALVKLD QAWWNVLSTS 451 FQYVCVLLAI DTPESLSHVA TAMKTLDNIT QILGTRIAFE AQKTAKLLLE 501 DSMKKKRQEI QQLEQATHQR SNLETTHLLD IDWDALLDPS DTLNFM*

Amino Acid Sequence (or in FASTA format)

       1  MASPGSTALP HKRQRVRKAC VPCRERKRKC NGKSPCEMCV AYGYVCHYID
      51  GRVPSASPQV QQVGETSPDT ESRPFVLPGI HRNEQPQPIN TQNVTSQNIV
     101  DPTKSRYTIQ HSAVAFPRCL GLELRSTNPP RLHSFAWHCG IRPEENPNSH
     151  VLLSDLVTKE EYYRISKVYF SVVHPIFDVV NPEQLAKNVE KYWDGDVKTL
     201  EYGAVIAGVI ALGSFFMGSL GHPREMDIVQ YAKGILDDPT FSRIPTVEQV
     251  SAWVLRTIYL RATSRPHVAW LASCVTIHLS EAIGLHHEID REDIAISNNV
     301  PPKRTTVVSE HTRRLFWCAW SINTILSYDY GRSSVTLNRI TCKPVKETDG
     351  NFTAHLVALA HLIPQDSVNA NAAQLLQALA AVHESPNAHP FLSLTKGDIC
     401  LSLYRRLRLL NHILDKNVVL QIIDIGNTAL SAAYALVKLD QAWWNVLSTS
     451  FQYVCVLLAI DTPESLSHVA TAMKTLDNIT QILGTRIAFE AQKTAKLLLE
     501  DSMKKKRQEI QQLEQATHQR SNLETTHLLD IDWDALLDPS DTLNFM*

external links for Rdr1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS
YGOB	CYC2008 (complexes)	Pfam domains
YOGY	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Rdr1p

1)	Hellauer K, et al. (2002) Zinc cluster protein Rdr1p is a transcriptional repressor of the PDR5 gene encoding a multidrug transporter. J Biol Chem 277(20):17671-6