YOR378W Protein Information Help

Systematic Name Yor378wp
ORF Classification Uncharacterized
Description Putative paralog of ATR1, but not required for boron tolerance; member of the DHA2 family of drug:H+ antiporters; YOR378W is not an essential gene (1, 2)
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 515
Molecular Weight (Da) 56,110
Isoelectric Point (pI) 8.34

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Yor378wp (InterPro)
Transmembrane Domains There are 12 total predicted transmembrane domains (TMHMM)
Physical Interactions There are 2 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000006ADAB | Q08902
MIPS: YOR378W
NCBI: 1420816 | 6324954 | 74627247 | NP_015023.1
GenBank/EMBL/DDBJ: DAA11137.1 | Z75286
External Classifications TC: 2.A.1.3 [The Drug:H+ Antiporter-2 (14 Spanner) (DHA2) Family]
Amino Acid Sequence (or in FASTA format)
 
       1  MSTSSSVTQK NLDTNAEALK KEDKVLSEFD IQDERPKSLL WESAFVGVLC
      51  SAQLMTQAGL GQSLAPLHII GNSFGTTNAG QLSWFASAYS LTVGTFILIA
     101  GRLGDIFGHK KFFVLGFFWY ALWSLLAGFS VYSNQIFFDC CRAFQGMGPA
     151  FLLPNAIAIL GRTYKPGRRK NMVFSLFGAS APGGFFLGAV FSSMLGQLAW
     201  WPWAYWIMGI ACFVLAVAGY FVIPHTPMPS RDASSFKLLE RIDFAGSVTG
     251  VVGLILFNFA WNQGPVVGWQ TPYTYALLIV GTFFLVIFAY IESRAAFPLL
     301  PFAALSSDTA FVLSCIAAGW ASFGIWIFYT WQFMEDSRGQ TPLLSSAQFS
     351  PVAISGFCAA VTTGFLLSHT PPSTVMLFAM TAFTVGTILI ATAPVHQTYW
     401  AQTFVSIIVM PWGMDMSFPA ATIMLSDSMP HEHQGLAASL VNTVVNYSIS
     451  IGLGIAGTIE SRVNDGGAKP LKGYRCSWYM GIGLSGLGIF VAATYAWSTF
     501  MKSKKRISEK QHFIE*

external links for Yor378wp
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS
YOGY CYC2008 (complexes) Pfam domains

Complexome TCDB

DIP YeastRC Structure Prediction (Seattle)

GeneMANIA

References cited on this page View Complete Literature Guide for Yor378wp
1) Gbelska Y, et al.  (2006) Evolution of gene families: the multidrug resistance transporter genes in five related yeast species. FEMS Yeast Res 6(3):345-55
2) Kaya A, et al.  (2009) Identification of a novel system for boron transport: Atr1 is a main boron exporter in yeast. Mol Cell Biol 29(13):3665-74