RPB8/YOR224C Protein Information

RPB8/YOR224C Protein Information

Standard Name	Rpb8p 1, 2
Systematic Name	Yor224cp
ORF Classification	Verified
Description	RNA polymerase subunit ABC14.5, common to RNA polymerases I, II, and III (3, 4, 5, 6)
Name Description	RNA Polymerase B 1
Gene Product	ABC14.5 7

Experimental Data
Molecules/cell	6210 8

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rpb8p (InterPro)
Physical Interactions	There are 164 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000053196 \| P20436 MIPS: YOR224C NCBI: 1050776 \| 110590861 \| 122920066 \| 122920081 \| 122920096 \| 122921035 \| 122921071 \| 122921087 \| 122921102 \| 122921114 \| 133340 \| 134104681 \| 134104696 \| 134104717 \| 134104729 \| 134104741 \| 1420518 \| 14278329 \| 14278340 \| 14278370 \| 146387189 \| 157829640 \| 160877780 \| 161172234 \| 161172247 \| 190613469 \| 194368739 \| 20150718 \| 224983597 \| 239781921 \| 239781934 \| 239781947 \| 239781960 \| 239781973 \| 239781987 \| 239782000 \| 239782013 \| 240104518 \| 254839448 \| 254839463 \| 254839478 \| 254839493 \| 254839508 \| 254839523 \| 254839538 \| 257471953 \| 257471968 \| 266618772 \| 269914557 \| 287826 \| 295982480 \| 295982493 \| 30749623 \| 30749744 \| 325053970 \| 325053985 \| 326634545 \| 343197461 \| 343197473 \| 343197485 \| 343197497 \| 343197509 \| 343197521 \| 343197533 \| 343197545 \| 343197557 \| 343197569 \| 343197581 \| 343781202 \| 34810560 \| 357380843 \| 359546297 \| 359546315 \| 359546332 \| 359546349 \| 359546366 \| 359546383 \| 359546399 \| 359546416 \| 374977886 \| 374977901 \| 380764986 \| 414145453 \| 414145466 \| 459358301 \| 46015420 \| 46015785 \| 51013625 \| 56965916 \| 56965928 \| 56966112 \| 56966126 \| 56966136 \| 56966146 \| 56966156 \| 58177171 \| 61679451 \| 61679468 \| 61679509 \| 61679522 \| 6324798 \| 83754250 \| NP_014867.1 GenBank/EMBL/DDBJ: DAA10995.1 \| AY693087 \| X53289 \| X92441 \| Z75132

Amino Acid Sequence (or in FASTA format)
1 MSNTLFDDIF QVSEVDPGRY NKVCRIEAAS TTQDQCKLTL DINVELFPVA 51 AQDSLTVTIA SSLNLEDTPA NDSSATRSWR PPQAGDRSLA DDYDYVMYGT 101 AYKFEEVSKD LIAVYYSFGG LLMRLEGNYR NLNNLKQENA YLLIRR*

external links for Rpb8p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Rpb8p

1)	Nonet M, et al. (1987) Eucaryotic RNA polymerase conditional mutant that rapidly ceases mRNA synthesis. Mol Cell Biol 7(5):1602-11
2)	Woychik NA, et al. (1990) Subunits shared by eukaryotic nuclear RNA polymerases. Genes Dev 4(3):313-23
3)	Archambault J and Friesen JD (1993) Genetics of eukaryotic RNA polymerases I, II, and III. Microbiol Rev 57(3):703-24
4)	Hampsey M (1998) Molecular genetics of the RNA polymerase II general transcriptional machinery. Microbiol Mol Biol Rev 62(2):465-503
5)	Myer VE and Young RA (1998) RNA polymerase II holoenzymes and subcomplexes. J Biol Chem 273(43):27757-60
6)	Cramer P, et al. (2000) Architecture of RNA polymerase II and implications for the transcription mechanism. Science 288(5466):640-9
7)	Sentenac A (1985) Eukaryotic RNA polymerases. CRC Crit Rev Biochem 18(1):31-90
8)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41