TOA1/YOR194C Protein Information

Standard Name	Toa1p 1
Systematic Name	Yor194cp
ORF Classification	Verified
Description	TFIIA large subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; homologous to largest and second largest subunits of human and Drosophila TFIIA (2)

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	286
Molecular Weight (Da)	32,201
Isoelectric Point (pI)	4.11

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Toa1p (InterPro)
Physical Interactions	There are 39 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001370F9 \| P32773 MIPS: YOR194C NCBI: 1420463 \| 1633308 \| 1633309 \| 172893 \| 38492531 \| 38492532 \| 418108 \| 51013897 \| 6324768 \| 73535265 \| NP_014837.1 GenBank/EMBL/DDBJ: DAA10969.1 \| AY693223 \| M85248 \| Z75102

Amino Acid Sequence (or in FASTA format)
1 MSNAEASRVY EIIVESVVNE VREDFENAGI DEQTLQDLKN IWQKKLTETK 51 VTTFSWDNQF NEGNINGVQN DLNFNLATPG VNSSEFNIKE ENTGNEGLIL 101 PNINSNNNIP HSGETNINTN TVEATNNSGA TLNTNTSGNT NADVTSQPKI 151 EVKPEIELTI NNANITTVEN IDDESEKKDD EEKEEDVEKT RKEKEQIEQV 201 KLQAKKEKRS ALLDTDEVGS ELDDSDDDYL ISEGEEDGPD ENLMLCLYDK 251 VTRTKARWKC SLKDGVVTIN RNDYTFQKAQ VEAEWV*

Amino Acid Sequence (or in FASTA format)

       1  MSNAEASRVY EIIVESVVNE VREDFENAGI DEQTLQDLKN IWQKKLTETK
      51  VTTFSWDNQF NEGNINGVQN DLNFNLATPG VNSSEFNIKE ENTGNEGLIL
     101  PNINSNNNIP HSGETNINTN TVEATNNSGA TLNTNTSGNT NADVTSQPKI
     151  EVKPEIELTI NNANITTVEN IDDESEKKDD EEKEEDVEKT RKEKEQIEQV
     201  KLQAKKEKRS ALLDTDEVGS ELDDSDDDYL ISEGEEDGPD ENLMLCLYDK
     251  VTRTKARWKC SLKDGVVTIN RNDYTFQKAQ VEAEWV*

external links for Toa1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Toa1p

1)	Ranish JA, et al. (1992) Isolation of two genes that encode subunits of the yeast transcription factor IIA. Science 255(5048):1127-9
2)	Hampsey M (1998) Molecular genetics of the RNA polymerase II general transcriptional machinery. Microbiol Mol Biol Rev 62(2):465-503