YRM1/YOR172W Protein Information

Standard Name	Yrm1p 1
Systematic Name	Yor172wp
ORF Classification	Verified
Description	Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrr1p, acting on an overlapping set of target genes (1)
Name Description	Yeast Reveromycin resistance Modulator 1

Experimental Data
Molecules/cell	125 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	786
Molecular Weight (Da)	91,083
Isoelectric Point (pI)	7.19

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Yrm1p (InterPro)
Physical Interactions	There are 7 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000006AA65 \| Q12340 MIPS: YOR172W NCBI: 1293731 \| 1420419 \| 2326816 \| 398365545 \| 51012865 \| 74655044 \| NP_014815.3 GenBank/EMBL/DDBJ: DAA10944.1 \| AY692707 \| U55021 \| Z75080 \| Z75081

Amino Acid Sequence (or in FASTA format)
1 MSKRGSLQDR ASPSEETVKK AQKRRKPIKS CAFCRKRKLR CDQQKPMCST 51 CKTRGRSGCL YTEKFTHKIE TKELFGSTPN IELLKRIEDL EKRLDDKELT 101 EKDVALSTSP FRNPYANFYY LQCKGSGRRI VYGPTSLRTH LSNDDNRFVN 151 TYNQLWSKVK IERNRWKARH KWTMKPETQL LEGPPLEKTG SDILQQVCNV 201 LPSFEQSSKI ITDFFNTELE TNEVSEVLDK TKIINDFTSS FLPSDELLPN 251 GERRIEKLLP STKKNYYKIG VILMILCIRH FYKNTPEEIE KFLIMLTGLS 301 TAKVYFIERA QFLLLKYYHR ELIWACGDDS HMISLVDLLC STAIMLGLHL 351 NIREIYKNQE NIVGSMESLE NLWVWIILSD FNVSLNIGRC LAINSSYFQV 401 DECENGERLP KNTNNYSSTV FFDQSNSCMG KLKRFLRLAR PMLDQIYDRS 451 AFPDLAENCK KLRNFVETEF HPISYYTDSE LISKVPLCEI KVLAQVLNLL 501 LTFYSLRYLI YKEKSVVLEN NILQTILVSF SLVINTTILC FNLDEKHFPE 551 FFDHNCVHLP PFMALSLVYT NFLFPRASTG FCAFLYHKLT LFEKGYYLSS 601 NIKDQEVTDW DLSTLNIPLD KAMNLLTAFK IHSDIFAKWS NDNNKQLRII 651 MARSYTFVIN IALESIYRAV LEKVIKYRTE VENTWLQQLQ DELNGSYSLT 701 DNVNTPIDPS LSDLGVTSAS PLAGNSPGLP PEEVRNNSEN ASHNNETGPI 751 ETELAQTISN EFWTAYNLGW EELMSQPDYK YLFDTQ*

Amino Acid Sequence (or in FASTA format)

       1  MSKRGSLQDR ASPSEETVKK AQKRRKPIKS CAFCRKRKLR CDQQKPMCST
      51  CKTRGRSGCL YTEKFTHKIE TKELFGSTPN IELLKRIEDL EKRLDDKELT
     101  EKDVALSTSP FRNPYANFYY LQCKGSGRRI VYGPTSLRTH LSNDDNRFVN
     151  TYNQLWSKVK IERNRWKARH KWTMKPETQL LEGPPLEKTG SDILQQVCNV
     201  LPSFEQSSKI ITDFFNTELE TNEVSEVLDK TKIINDFTSS FLPSDELLPN
     251  GERRIEKLLP STKKNYYKIG VILMILCIRH FYKNTPEEIE KFLIMLTGLS
     301  TAKVYFIERA QFLLLKYYHR ELIWACGDDS HMISLVDLLC STAIMLGLHL
     351  NIREIYKNQE NIVGSMESLE NLWVWIILSD FNVSLNIGRC LAINSSYFQV
     401  DECENGERLP KNTNNYSSTV FFDQSNSCMG KLKRFLRLAR PMLDQIYDRS
     451  AFPDLAENCK KLRNFVETEF HPISYYTDSE LISKVPLCEI KVLAQVLNLL
     501  LTFYSLRYLI YKEKSVVLEN NILQTILVSF SLVINTTILC FNLDEKHFPE
     551  FFDHNCVHLP PFMALSLVYT NFLFPRASTG FCAFLYHKLT LFEKGYYLSS
     601  NIKDQEVTDW DLSTLNIPLD KAMNLLTAFK IHSDIFAKWS NDNNKQLRII
     651  MARSYTFVIN IALESIYRAV LEKVIKYRTE VENTWLQQLQ DELNGSYSLT
     701  DNVNTPIDPS LSDLGVTSAS PLAGNSPGLP PEEVRNNSEN ASHNNETGPI
     751  ETELAQTISN EFWTAYNLGW EELMSQPDYK YLFDTQ*

external links for Yrm1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS	YeastRC Public Image Repository
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Yrm1p

1)	Lucau-Danila A, et al. (2003) Competitive promoter occupancy by two yeast paralogous transcription factors controlling the multidrug resistance phenomenon. J Biol Chem 278(52):52641-50
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41