ISN1/YOR155C Protein Information

Standard Name	Isn1p 1
Systematic Name	Yor155cp
ORF Classification	Verified
Description	Inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase, catalyzes the breakdown of IMP to inosine, does not show similarity to known 5'-nucleotidases from other organisms (1)
Name Description	IMP-Specific 5'-Nucleotidase 1

Experimental Data
Molecules/cell	1590 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	450
Molecular Weight (Da)	51,329
Isoelectric Point (pI)	5.17

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Isn1p (InterPro)
Physical Interactions	There are 8 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000006B99A \| Q99312 MIPS: YOR155C NCBI: 1293715 \| 1420387 \| 398365441 \| 74644568 \| NP_014798.3 GenBank/EMBL/DDBJ: DAA10928.1 \| U55020 \| Z75063
External Classifications	EC: 3.1.3.- [Phosphoric Monoester Hydrolases]

Amino Acid Sequence (or in FASTA format)
1 MSSRYRVEYH LKSHRKDEFI DWVKGLLASP FVLHAVSHEG DYNDDLATTQ 51 RVRSQYADIF KDIEGLIKDK IEFDSRNMSQ DEIEDGASSQ SLNILGQSRL 101 NLLVPSIGTF FTELPLEQAF LWEDSQRAIS ARRMVAPSFN DIRHILNTAQ 151 IFHFKKQENL HNGKVLRLVT FDGDVTLYED GGSLVYTNPV IPYILKLLRC 201 GINVGIVTAA GYDEAGTYEN RLKGLIVALH DSTDIPVSQK QNLTIMGGES 251 SYLFRYYEDP EEDNFGFRQI DKEEWLLPRM KAWSLEDVEK TLDFAERTLN 301 RLRKRLNLPS EISIIRKVRA VGIVPGERYD EASKRQVPVK LDREQLEEIV 351 LTLQNTLESF APSRRIQFSC FDGGSDVWCD IGGKDLGVRS LQQFYNPESP 401 IQPSETLHVG DQFAPVGSAN DFKARLAGCT LWIASPQETV NYLHRLLETD 451 *

Amino Acid Sequence (or in FASTA format)

       1  MSSRYRVEYH LKSHRKDEFI DWVKGLLASP FVLHAVSHEG DYNDDLATTQ
      51  RVRSQYADIF KDIEGLIKDK IEFDSRNMSQ DEIEDGASSQ SLNILGQSRL
     101  NLLVPSIGTF FTELPLEQAF LWEDSQRAIS ARRMVAPSFN DIRHILNTAQ
     151  IFHFKKQENL HNGKVLRLVT FDGDVTLYED GGSLVYTNPV IPYILKLLRC
     201  GINVGIVTAA GYDEAGTYEN RLKGLIVALH DSTDIPVSQK QNLTIMGGES
     251  SYLFRYYEDP EEDNFGFRQI DKEEWLLPRM KAWSLEDVEK TLDFAERTLN
     301  RLRKRLNLPS EISIIRKVRA VGIVPGERYD EASKRQVPVK LDREQLEEIV
     351  LTLQNTLESF APSRRIQFSC FDGGSDVWCD IGGKDLGVRS LQQFYNPESP
     401  IQPSETLHVG DQFAPVGSAN DFKARLAGCT LWIASPQETV NYLHRLLETD
     451  *

external links for Isn1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Isn1p

1)	Itoh R, et al. (2003) The yeast ISN1 (YOR155c) gene encodes a new type of IMP-specific 5'-nucleotidase. BMC Biochem 4():4
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41