CEX1/YOR112W Protein Information

Standard Name	Cex1p 1
Systematic Name	Yor112wp
ORF Classification	Verified
Description	Cytoplasmic component of the nuclear aminoacylation-dependent tRNA export pathway; interacts with nuclear pore component Nup116p; copurifies with tRNA export receptors Los1p and Msn5p, as well as eIF-1a and the RAN GTPase Gsp1p (1)
Name Description	Cytoplasmic EXport protein 1

Experimental Data
Molecules/cell	1360 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	761
Molecular Weight (Da)	84,768
Isoelectric Point (pI)	5.13

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Cex1p (InterPro)
Physical Interactions	There are 25 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000069D69 \| Q12453 MIPS: YOR112W NCBI: 1050818 \| 1164957 \| 1420301 \| 6324686 \| 74676602 \| NP_014755.1 GenBank/EMBL/DDBJ: DAA10887.1 \| X90518 \| X94335 \| Z75020

Amino Acid Sequence (or in FASTA format)
1 MNFSSIFKSI SNFQFPYTIE ETAITETALW QCFDGTRKAD SLPVTVFKAK 51 RSPENESLIL NAVHKSKILK IPGLCTVLET FDSDPQSTFI VTERVVPFPW 101 DNLGSLSQNK FGVELGISQL LATLGFLKNF VLGTLSKDSV FINIKGEWVL 151 FGLELCSSKE GLSAFEFASR ARSYYNIIGS QLPCEDPNTI DSMGLGLLIK 201 SLMAPSCLPK DWIVNVNMIS DGKITIENFR KRLENTETWR SNPLINFYQE 251 LRELHIKDPQ GKLVVMSNLE NLYLESREIF RNLTPGMIEN FIIPELCEII 301 KLLMTQSISS AASPIGMNFN ASHKLVPFLA IVLDLTSETN TFPVGFNDLI 351 TQSFKLPDRQ VRFLLLIYLP KLIGPLSKSE ISSRIYPHFI QGLTDSDATL 401 RLQTLKTIPC IVSCLTERQL NNELLRFLAK TQVDSDVEIR TWTVIIISKI 451 STILSTSVGN RSNILATAFT KSLKDPQVKP RLAALYGLEK SIELFDVNTI 501 ANKILTVIAP GLLDKSPIVR GRAKILFEEY LEKLEKEAQL IQTNDSTADS 551 EDVKDIDFEN YGCDEEDMNK EDNLLAAQFL NNLRLNSPSA TTPSNITESE 601 IDSAQDGSGW DDLSDTDGFI TNGTTESFDE TTNPVTTAST PKLFGKPIKI 651 NKSWNDELND DGWIQDESGP SKVPQKHTRP QNSTLAKSIA PSSRLSIKKK 701 KTTILAPRNI ASNSTVTTKS SLSNKTARSK PISSIRGSVT KKGNVDGWDD 751 DGDSDSWDTN W*

Amino Acid Sequence (or in FASTA format)

       1  MNFSSIFKSI SNFQFPYTIE ETAITETALW QCFDGTRKAD SLPVTVFKAK
      51  RSPENESLIL NAVHKSKILK IPGLCTVLET FDSDPQSTFI VTERVVPFPW
     101  DNLGSLSQNK FGVELGISQL LATLGFLKNF VLGTLSKDSV FINIKGEWVL
     151  FGLELCSSKE GLSAFEFASR ARSYYNIIGS QLPCEDPNTI DSMGLGLLIK
     201  SLMAPSCLPK DWIVNVNMIS DGKITIENFR KRLENTETWR SNPLINFYQE
     251  LRELHIKDPQ GKLVVMSNLE NLYLESREIF RNLTPGMIEN FIIPELCEII
     301  KLLMTQSISS AASPIGMNFN ASHKLVPFLA IVLDLTSETN TFPVGFNDLI
     351  TQSFKLPDRQ VRFLLLIYLP KLIGPLSKSE ISSRIYPHFI QGLTDSDATL
     401  RLQTLKTIPC IVSCLTERQL NNELLRFLAK TQVDSDVEIR TWTVIIISKI
     451  STILSTSVGN RSNILATAFT KSLKDPQVKP RLAALYGLEK SIELFDVNTI
     501  ANKILTVIAP GLLDKSPIVR GRAKILFEEY LEKLEKEAQL IQTNDSTADS
     551  EDVKDIDFEN YGCDEEDMNK EDNLLAAQFL NNLRLNSPSA TTPSNITESE
     601  IDSAQDGSGW DDLSDTDGFI TNGTTESFDE TTNPVTTAST PKLFGKPIKI
     651  NKSWNDELND DGWIQDESGP SKVPQKHTRP QNSTLAKSIA PSSRLSIKKK
     701  KTTILAPRNI ASNSTVTTKS SLSNKTARSK PISSIRGSVT KKGNVDGWDD
     751  DGDSDSWDTN W*

external links for Cex1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Cex1p

1)	McGuire AT and Mangroo D (2007) Cex1p is a novel cytoplasmic component of the Saccharomyces cerevisiae nuclear tRNA export machinery. EMBO J 26(2):288-300
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41