RKI1/YOR095C Protein Information

Standard Name	Rki1p
Systematic Name	Yor095cp
ORF Classification	Verified
Description	Ribose-5-phosphate ketol-isomerase, catalyzes the interconversion of ribose 5-phosphate and ribulose 5-phosphate in the pentose phosphate pathway; participates in pyridoxine biosynthesis (1, 2)
Name Description	Ribose-5-phosphate Ketol-Isomerase 1

Experimental Data
Molecules/cell	5680 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	258
Molecular Weight (Da)	28,258
Isoelectric Point (pI)	5.77

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rki1p (InterPro)
Physical Interactions	There are 11 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000134642 \| Q12189 MIPS: YOR095C NCBI: 1164942 \| 1420269 \| 6226036 \| 6324669 \| 75765507 \| NP_014738.1 GenBank/EMBL/DDBJ: DAA10872.1 \| X94335 \| Z75003
External Classifications	EC: 5.3.1.6 [Ribose-5-phosphate isomerase]

Amino Acid Sequence (or in FASTA format)
1 MAAGVPKIDA LESLGNPLED AKRAAAYRAV DENLKFDDHK IIGIGSGSTV 51 VYVAERIGQY LHDPKFYEVA SKFICIPTGF QSRNLILDNK LQLGSIEQYP 101 RIDIAFDGAD EVDENLQLIK GGGACLFQEK LVSTSAKTFI VVADSRKKSP 151 KHLGKNWRQG VPIEIVPSSY VRVKNDLLEQ LHAEKVDIRQ GGSAKAGPVV 201 TDNNNFIIDA DFGEISDPRK LHREIKLLVG VVETGLFIDN ASKAYFGNSD 251 GSVEVTEK*

Amino Acid Sequence (or in FASTA format)

       1  MAAGVPKIDA LESLGNPLED AKRAAAYRAV DENLKFDDHK IIGIGSGSTV
      51  VYVAERIGQY LHDPKFYEVA SKFICIPTGF QSRNLILDNK LQLGSIEQYP
     101  RIDIAFDGAD EVDENLQLIK GGGACLFQEK LVSTSAKTFI VVADSRKKSP
     151  KHLGKNWRQG VPIEIVPSSY VRVKNDLLEQ LHAEKVDIRQ GGSAKAGPVV
     201  TDNNNFIIDA DFGEISDPRK LHREIKLLVG VVETGLFIDN ASKAYFGNSD
     251  GSVEVTEK*

external links for Rki1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Candida (CGD)	BioPIXIE	MIPS	YeastGFP
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Rki1p

1)	Miosga T and Zimmermann FK (1996) Cloning and characterization of the first two genes of the non-oxidative part of the Saccharomyces cerevisiae pentose-phosphate pathway. Curr Genet 30(5):404-9
2)	Kondo H, et al. (2004) Pyridoxine biosynthesis in yeast: participation of ribose 5-phosphate ketol-isomerase. Biochem J 379(Pt 1):65-70
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41