TOM6/YOR045W Protein Information 
| Standard Name | Tom6p 1 |
|---|---|
| Systematic Name | Yor045wp |
| Alias | Isp6p 2 , Mom8bp 3 |
| ORF Classification | Verified |
| Description | Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex (4, 5, 6, 7) |
| Name Description | Translocase of the Outer Mitochondrial membrane 1 |
| Click on image for expanded interactive view |
|---|
| Post-translational Modifications | PhosphoGRID | PhosphoPep Database |
|---|---|
| Domains/motifs | See the graphical view and list of proteins that share domains/motifs in common with Tom6p (InterPro) |
| Transmembrane Domains | There are 1 total predicted transmembrane domains (TMHMM) |
| Physical Interactions | There are 8 total physical interactions (BioGRID) |
| Homologs | PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer |
| External Sequence Databases |
EBI: UPI0000130C87 | P33448 MIPS: YOR045W NCBI: 1420173 | 395230 | 462424 | 51013553 | 6324619 | NP_014688.1 GenBank/EMBL/DDBJ: DAA10827.1 | AY693051 | Z22815 | Z74953 |
external links for Tom6p
| Homologs | Interaction Resources | Protein databases/Other | Localization Resources |
|---|---|---|---|
| BLASTP (NCBI) | BioGRID | SCOP Superfamily | YPL+ |
| Ashbya (AGD) | BOND | GPMdb (Mass Spec.) | YeastGFP |
| Candida (CGD) | BioPIXIE | MIPS | YeastRC Public Image Repository |
| Candida (CandidaDB) | CYC2008 (complexes) | Pfam domains | |
| YGOB | Complexome | ||
| YOGY | DIP | ||
| GeneMANIA | |||
| YeastRC Two-Hybrid (Seattle) |
References cited on this page View Complete Literature Guide for Tom6p
| 1) | Pfanner N, et al. (1996) Uniform nomenclature for the protein transport machinery of the mitochondrial membranes. Trends Biochem Sci 21(2):51-2 |
| 2) | Kassenbrock CK, et al. (1993) Genetic and biochemical characterization of ISP6, a small mitochondrial outer membrane protein associated with the protein translocation complex. EMBO J 12(8):3023-34 |
| 3) | Alconada A, et al. (1995) The mitochondrial receptor complex: the small subunit Mom8b/Isp6 supports association of receptors with the general insertion pore and transfer of preproteins. Mol Cell Biol 15(11):6196-205 |
| 4) | Model K, et al. (2001) Multistep assembly of the protein import channel of the mitochondrial outer membrane. Nat Struct Biol 8(4):361-70 |
| 5) | Meisinger C, et al. (1999) The preprotein translocase of the outer mitochondrial membrane: receptors and a general import pore. Cell Mol Life Sci 56(9-10):817-24 |
| 6) | Ryan MT, et al. (2000) The transport machinery for the import of preproteins across the outer mitochondrial membrane. Int J Biochem Cell Biol 32(1):13-21 |
| 7) | Pfanner N, et al. (2004) Assembling the mitochondrial outer membrane. Nat Struct Mol Biol 11(11):1044-8 |
