TIR4/YOR009W Protein Information

Standard Name	Tir4p
Systematic Name	Yor009wp
ORF Classification	Verified
Description	Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth; transcription is also induced by cold shock (1)
Name Description	TIp1-Related 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	487
Molecular Weight (Da)	47,848
Isoelectric Point (pI)	3.87

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Tir4p (InterPro)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 5 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000006A42C \| Q12218 MIPS: YOR009W NCBI: 1151005 \| 1420104 \| 6324583 \| 74655039 \| NP_014652.1 GenBank/EMBL/DDBJ: DAA10792.1 \| U43491 \| Z74917

Amino Acid Sequence (or in FASTA format)
1 MAYSKITLLA ALAAIAYAQT QAQINELNVV LDDVKTNIAD YITLSYTPNS 51 GFSLDQMPAG IMDIAAQLVA NPSDDSYTTL YSEVDFSAVE HMLTMVPWYS 101 SRLLPELEAM DASLTTSSSA ATSSSEVASS SIASSTSSSV APSSSEVVSS 151 SVAPSSSEVV SSSVAPSSSE VVSSSVASSS SEVASSSVAP SSSEVVSSSV 201 ASSSSEVASS SVAPSSSEVV SSSVAPSSSE VVSSSVASSS SEVASSSVAP 251 SSSEVVSSSV ASSTSEATSS SAVTSSSAVS SSTESVSSSS VSSSSAVSSS 301 EAVSSSPVSS VVSSSAGPAS SSVAPYNSTI ASSSSTAQTS ISTIAPYNST 351 TTTTPASSAS SVIISTRNGT TVTETDNTLV TKETTVCDYS STSAVPASTT 401 GYNNSTKVST ATICSTCKEG TSTATDFSTL KTTVTVCDSA CQAKKSATVV 451 SVQSKTTGIV EQTENGAAKA VIGMGAGALA AVAAMLL*

Amino Acid Sequence (or in FASTA format)

       1  MAYSKITLLA ALAAIAYAQT QAQINELNVV LDDVKTNIAD YITLSYTPNS
      51  GFSLDQMPAG IMDIAAQLVA NPSDDSYTTL YSEVDFSAVE HMLTMVPWYS
     101  SRLLPELEAM DASLTTSSSA ATSSSEVASS SIASSTSSSV APSSSEVVSS
     151  SVAPSSSEVV SSSVAPSSSE VVSSSVASSS SEVASSSVAP SSSEVVSSSV
     201  ASSSSEVASS SVAPSSSEVV SSSVAPSSSE VVSSSVASSS SEVASSSVAP
     251  SSSEVVSSSV ASSTSEATSS SAVTSSSAVS SSTESVSSSS VSSSSAVSSS
     301  EAVSSSPVSS VVSSSAGPAS SSVAPYNSTI ASSSSTAQTS ISTIAPYNST
     351  TTTTPASSAS SVIISTRNGT TVTETDNTLV TKETTVCDYS STSAVPASTT
     401  GYNNSTKVST ATICSTCKEG TSTATDFSTL KTTVTVCDSA CQAKKSATVV
     451  SVQSKTTGIV EQTENGAAKA VIGMGAGALA AVAAMLL*

external links for Tir4p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Tir4p

1)	Abramova N, et al. (2001) Reciprocal regulation of anaerobic and aerobic cell wall mannoprotein gene expression in Saccharomyces cerevisiae. J Bacteriol 183(9):2881-7