IMA2/YOL157C Protein Information Help

Standard Name Ima2p 1, 2
Systematic Name Yol157cp
ORF Classification Verified
Description Isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase); specificity for isomaltase, alpha-methylglucoside, and palatinose; not required for isomaltose utilization, but Ima2p overexpression allows the ima1 null mutant to grow on isomaltose (1, 2, 3)
Name Description IsoMAltase 1, 2
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 589
Molecular Weight (Da) 68,624
Isoelectric Point (pI) 5.29

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ima2p (InterPro)
Physical Interactions There are 1 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000006C408 | Q08295
MIPS: YOL157C
NCBI: 6324416 | 74627241 | NP_014485.1
GenBank/EMBL/DDBJ: DAA10629.1 | Z74899
External Classifications EC: 3.2.1.10 [Oligo-1,6-glucosidase]
EC: 3.2.1.20 [Alpha-glucosidase]
Amino Acid Sequence (or in FASTA format)
 
       1  MTISSAHPET EPKWWKEATI YQIYPASFKD SNNDGWGDMK GIASKLEYIK
      51  ELGADAIWIS PFYDSPQDDM GYDIANYEKV WPTYGTNEDC FALIEKTHKL
     101  GMKFITDLVI NHCSSEHEWF KESRSSKTNP KRDWFFWRPP KGYDAEGKPI
     151  PPNNWRSYFG GSAWTFDEKT QEFYLRLFCS TQPDLNWENE DCRKAIYESA
     201  VGYWLDHGVD GFRIDVGSLY SKVAGLPDAP VIDENSKWQP SDPFTMNGPR
     251  IHEFHQEMNK FIRNRVKDGR EIMTVGEMQH ATDETKRLYT SASRHELSEL
     301  FNFSHTDVGT SPKFRQNLIP YELKDWKVAL AELFRYVNGT DCWSTIYLEN
     351  HDQPRSITRF GDDSPKNRVI SGKLLSVLLV SLSGTLYVYQ GQELGEINFK
     401  NWPIEKYEDV EVRNNYDAIK EEHGENSKEM KRFLEAIALI SRDHARTPMQ
     451  WSREEPNAGF SGPNAKPWFY LNESFREGIN AEDESKDPNS VLNFWKEALR
     501  FRKAHKDITV YGYDFEFIDL DNKKLFSFTK KYDNKTLFAA LNFSSDSIDF
     551  TIPNNSSSFK LEFGNYPRSE VDASSRTLKP WEGRIYISE*

external links for Ima2p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
YGOB BioPIXIE MIPS YeastGFP
YOGY CYC2008 (complexes) Pfam domains

Complexome YeastRC Structure Prediction (Seattle)

GeneMANIA

References cited on this page View Complete Literature Guide for Ima2p
1) Teste MA, et al.  (2010) Characterization of a New Multigene Family Encoding Isomaltases in the Yeast Saccharomyces cerevisiae, the IMA Family. J Biol Chem 285(35):26815-24
2) Naumoff DG and Naumov GI  (2010) Discovery of a novel family of alpha-glucosidase IMA genes in yeast Saccharomyces cerevisiae. Dokl Biochem Biophys 432():114-6
3) Brown CA, et al.  (2010) Rapid expansion and functional divergence of subtelomeric gene families in yeasts. Curr Biol 20(10):895-903