HXT11/YOL156W Protein Information Help

Standard Name Hxt11p
Systematic Name Yol156wp
Alias Lgt3p
ORF Classification Verified
Description Putative hexose transporter that is nearly identical to Hxt9p, has similarity to major facilitator superfamily (MFS) transporters and is involved in pleiotropic drug resistance (1, 2)
Name Description HeXose Transporter
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 567
Molecular Weight (Da) 62,732
Isoelectric Point (pI) 8.54

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Hxt11p (InterPro)
Transmembrane Domains There are 11 total predicted transmembrane domains (TMHMM)
Physical Interactions There are 6 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000012CFBD | P54862
MIPS: YOL156W
NCBI: 1177621 | 1420066 | 1708368 | 575724 | 6324417 | NP_014486.1
GenBank/EMBL/DDBJ: DAA10630.1 | X82621 | X89715 | Z74898
External Classifications TC: 2.A.1.1 [The Sugar Porter (SP) Family]
Amino Acid Sequence (or in FASTA format)
 
       1  MSGVNNTSAN ELSTTMSNSN SAVGAPSVKT EHGDSKNSLN LDANEPPIDL
      51  PQKPLSAYTT VAILCLMIAF GGFIFGWDTG TISGFVNLSD FIRRFGQKND
     101  KGTYYLSKVR MGLIVSIFNI GCAIGGIVLS KVGDIYGRRI GLITVTAIYV
     151  VGILIQITSI NKWYQYFIGR IISGLGVGGI AVLSPMLISE VAPKHIRGTL
     201  VQLYQLMGTM GIFLGYCTNY GTKNYHNATQ WRVGLGLCFA WATFMVSGMM
     251  FVPESPRYLI EVGKDEEAKR SLSKSNKVSV DDPALLVEYD TIKAGIELEK
     301  LAGNASWSEL LSTKTKVFQR VLMGVMIQSL QQLTGDNYFF YYGTTIFKSV
     351  GLKDSFQTSI IIGVVNFFSS FIAVYTIERF GRRTCLLWGA ASMLCCFAVF
     401  ASVGVTKLWP QGSSHQDITS QGAGNCMIVF TMFFIFSFAT TWAGGCYVIV
     451  SETFPLRVKS RGMAIATAAN WMWGFLISFF TPFITGAINF YYGYVFLGCL
     501  VFAYFYVFFF VPETKGLTLE EVNTMWLEGV PAWKSASWVP PERRTADYDA
     551  DAIDHDNRPI YKRFFSS*

external links for Hxt11p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS
YOGY CYC2008 (complexes) Pfam domains

Complexome TCDB

DIP YeastRC Structure Prediction (Seattle)

GeneMANIA

References cited on this page View Complete Literature Guide for Hxt11p
1) Ozcan S and Johnston M  (1999) Function and regulation of yeast hexose transporters. Microbiol Mol Biol Rev 63(3):554-69
2) Nourani A, et al.  (1997) Multiple-drug-resistance phenomenon in the yeast Saccharomyces cerevisiae: involvement of two hexose transporters. Mol Cell Biol 17(9):5453-60