RPL25/YOL127W Protein Information Help

Standard Name Rpl25p
Systematic Name Yol127wp
ORF Classification Verified
Description Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23 (1, 2, 3, 4, 5, 6)
Name Description Ribosomal Protein of the Large subunit
Gene Product L23 6 , L25 2 , YL25 2 , rpl6L 2
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 142
Molecular Weight (Da) 15,757
Isoelectric Point (pI) 10.94

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Rpl25p (InterPro)
Physical Interactions There are 173 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000036D01 | P04456
MIPS: YOL127W
NCBI: 1209714 | 1420011 | 1710524 | 270346348 | 270346363 | 315113320 | 315113546 | 315113593 | 365767274 | 365767316 | 410562502 | 4326 | 49258858 | 6324445 | NP_014514.1
GenBank/EMBL/DDBJ: DAA10657.1 | U41293 | X01014 | Z74869
Amino Acid Sequence (or in FASTA format)
 
       1  MAPSAKATAA KKAVVKGTNG KKALKVRTSA TFRLPKTLKL ARAPKYASKA
      51  VPHYNRLDSY KVIEQPITSE TAMKKVEDGN ILVFQVSMKA NKYQIKKAVK
     101  ELYEVDVLKV NTLVRPNGTK KAYVRLTADY DALDIANRIG YI*

external links for Rpl25p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) BioPIXIE MIPS YeastGFP
Candida (CGD) CYC2008 (complexes) Pfam domains
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Rpl25p
1) Kooi EA, et al.  (1994) Mutational analysis of the C-terminal region of Saccharomyces cerevisiae ribosomal protein L25 in vitro and in vivo demonstrates the presence of two distinct functional elements. J Mol Biol 240(3):243-55
2) Planta RJ and Mager WH  (1998) The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae. Yeast 14(5):471-7
3) Woudt LP, et al.  (1986) Conserved sequence elements upstream of the gene encoding yeast ribosomal protein L25 are involved in transcription activation. EMBO J 5(5):1037-40
4) van Beekvelt CA, et al.  (2000) Domain III of Saccharomyces cerevisiae 25 S ribosomal RNA: its role in binding of ribosomal protein L25 and 60 S subunit formation. J Mol Biol 296(1):7-17
5) Lecompte O, et al.  (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90
6) Jenner L, et al.  (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol 22(6):759-67