MCH4/YOL119C Protein Information

Standard Name	Mch4p 1
Systematic Name	Yol119cp
ORF Classification	Verified
Description	Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport (1)
Name Description	MonoCarboxylate transporter Homologue 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	501
Molecular Weight (Da)	54,706
Isoelectric Point (pI)	9.15

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Mch4p (InterPro)
Transmembrane Domains	There are 12 total predicted transmembrane domains (TMHMM)
Physical Interactions	There are 4 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000069EE8 \| Q08268 MIPS: YOL119C NCBI: 1419995 \| 1550726 \| 32469677 \| 6324453 \| NP_014522.1 GenBank/EMBL/DDBJ: DAA10665.1 \| X95258 \| Z74861

Amino Acid Sequence (or in FASTA format)
1 MLNIPIIANS KRFLFSKDHE AQSTRDHDVE LETREGPSSG YNPNFNAADA 51 ILKKNSDQVD LDVNKLTNVT SRVLNTPEAS LIYDDDREFP DGGLKAWLVV 101 FGAFMGLVPV FGLINSLGAI ESYISKHQLA NISSSTISWI FSLYLAISFL 151 SCILSGGYFD RNGSIGLMCT GTVIYAGGLF ALANCKSVWQ FILAFSVCSG 201 LGTGILMTPL IGTVATWFLK RRGIATSIST MGGSIGGIVF PIMLRKLYKE 251 VGFQWAIRIL SFICLTCLIC ASVLARERTK PVVQPFKSKA EVAKWYISSV 301 FNWRYFLEGK FLFVAIGASF AESSLTSCAT YLASYSMTRG NTENVAYTMI 351 TASNAVGILG RYIPGYFADK FIGRFNVEII TISMAALFNF VMWLPFGGNT 401 KVLWAYVCLW GFSTGSILSL TPVCIGQISK TTDFGKRYAT VYLLQALVTI 451 PVLPIGGTLI GKGTVANYNH FIIFNSALMA AGAACYIISR HICVGAKLCK 501 F*

Amino Acid Sequence (or in FASTA format)

       1  MLNIPIIANS KRFLFSKDHE AQSTRDHDVE LETREGPSSG YNPNFNAADA
      51  ILKKNSDQVD LDVNKLTNVT SRVLNTPEAS LIYDDDREFP DGGLKAWLVV
     101  FGAFMGLVPV FGLINSLGAI ESYISKHQLA NISSSTISWI FSLYLAISFL
     151  SCILSGGYFD RNGSIGLMCT GTVIYAGGLF ALANCKSVWQ FILAFSVCSG
     201  LGTGILMTPL IGTVATWFLK RRGIATSIST MGGSIGGIVF PIMLRKLYKE
     251  VGFQWAIRIL SFICLTCLIC ASVLARERTK PVVQPFKSKA EVAKWYISSV
     301  FNWRYFLEGK FLFVAIGASF AESSLTSCAT YLASYSMTRG NTENVAYTMI
     351  TASNAVGILG RYIPGYFADK FIGRFNVEII TISMAALFNF VMWLPFGGNT
     401  KVLWAYVCLW GFSTGSILSL TPVCIGQISK TTDFGKRYAT VYLLQALVTI
     451  PVLPIGGTLI GKGTVANYNH FIIFNSALMA AGAACYIISR HICVGAKLCK
     501  F*

external links for Mch4p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS
YGOB	CYC2008 (complexes)	Pfam domains
YOGY	Complexome	YeastRC Structure Prediction (Seattle)
	GeneMANIA

References cited on this page View Complete Literature Guide for Mch4p

1)	Makuc J, et al. (2001) The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane. Yeast 18(12):1131-43