HAL9/YOL089C Protein Information Help

Standard Name Hal9p 1
Systematic Name Yol089cp
ORF Classification Verified
Description Putative transcription factor containing a zinc finger; overexpression increases salt tolerance through increased expression of the ENA1 (Na+/Li+ extrusion pump) gene while gene disruption decreases both salt tolerance and ENA1 expression; HAL9 has a paralog, TBS1, that arose from the whole genome duplication (1, 2)
Name Description HALotolerance 1
Experimental Data
Molecules/cell 238 3
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 1,030
Molecular Weight (Da) 117,925
Isoelectric Point (pI) 7.67

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Hal9p (InterPro)
Physical Interactions There are 9 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000006C06B | Q12180
MIPS: YOL089C
NCBI: 1419932 | 600469 | 6324483 | 74645031 | NP_014552.1 | NM_001183343.1
GenBank/EMBL/DDBJ: DAA10695.1 | X83121 | Z74831
Amino Acid Sequence (or in FASTA format)
 
       1  MENQGGDYSP NGFSNSASNM NAVFNNEITG RSDISNVNHQ TGTPRLVPET
      51  QIWSMPVPDQ LMTMPNRENT LMTGSTIGPN IPMNVAYPNT IYSPTEHQSQ
     101  FQTQQNRDIS TMMEHTNSND MSGSGKNLKK RVSKACDHCR KRKIRCDEVD
     151  QQTKKCSNCI KFQLPCTFKH RDEILKKKRK LEIKHHATPG ESLQTSNSIS
     201  NPVASSSVPN SGRFELLNGN SPLESNIIDK VSNIQNNLNK KMNSKIEKLD
     251  RKMSYIIDSV ARLEWLLDKA VKKQEGKYKE KNNLPKPARK IYSTALLTAQ
     301  KLYWFKQSLG VKASNEEFLS PISEILSISL KWYATQMKKF MDLSSPAFFS
     351  SEIILYSLPP KKQAKRLLEN FHATLLSSVT GIISLKECLD LAEKYYSESG
     401  EKLTYPEHLL LNVCLCSGAS ATQSIIRGDS KFLRKDRYDP TSQELKKIEN
     451  VALLNAMYYY HKLSTICSGT RTLQALLLLN RYFQLTYDTE LANCILGTAI
     501  RLAVDMELNR KSSYKSLDFE EAIRRRRMWW HCFCTDKLYS LMLSRPPIVG
     551  ERDMDMLTDQ NYYEVIKTNI LPDLIDKKED LDKITDVNSA LNVVVNFCQH
     601  ISLFISYYVS KLVSIESKIY STCFAVRSTL DLSFDAMLDK IKDLNDSLNN
     651  WRDNLHVSMK LKSYKQYLSV LYAQKSQENP ALSFEIACSR VLNCHFRALY
     701  SKVILSMMTT SLLIDNERLY KGSRHDIPQL FILFSSQYLN ASKEMLQLFQ
     751  GINYQAHMYN EVMYQFSTAM FVLFFYVVDN MNDLKKKGEV KEIIDILKKS
     801  YDRLVGENDE QLLFDNVKWN TLIVFYSHFL KYVLQRYHAL NDSTSIFDSK
     851  PYDETITKVI MHSRKIKDET VDQLIMSLKS YGSLHSLQKG NEADLADDGL
     901  NTNDISSEDF AEEAPINLFG ELSVEILKLL KSHSPISNFG DLSPSSNRKG
     951  ISDDSSLYPI RSDLTSLVYP IHSSDTGDTL SSGLETPENS NFNSDSGIKE
    1001  DFEAFRALLP LGKLIYDRDY SFVNTFRDYE *

external links for Hal9p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Candida (CGD) BioPIXIE MIPS YeastRC Public Image Repository
YGOB CYC2008 (complexes) Pfam domains
YOGY Complexome YeastRC Structure Prediction (Seattle)

GeneMANIA

References cited on this page View Complete Literature Guide for Hal9p
1) Mendizabal I, et al.  (1998) Yeast putative transcription factors involved in salt tolerance. FEBS Lett 425(2):323-8
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41