PHM7/YOL084W Protein Information Help

Standard Name Phm7p 1
Systematic Name Yol084wp
ORF Classification Verified
Description Protein of unknown function; expression is regulated by phosphate levels; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole; protein abundance increases in response to DNA replication stress (1, 2, 3)
Name Description PHosphate Metabolism 1
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 991
Molecular Weight (Da) 112,545
Isoelectric Point (pI) 8.87

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Phm7p (InterPro)
Transmembrane Domains There are 10 total predicted transmembrane domains (TMHMM)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 2 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000006AF11 | Q12252
MIPS: YOL084W
NCBI: 1419922 | 600474 | 6324488 | 74645037 | NP_014557.1
GenBank/EMBL/DDBJ: DAA10700.1 | X83121 | Z74826
Amino Acid Sequence (or in FASTA format)
 
       1  MADSSSTSAF ISTLIIYGLT AVVFVWLFLL LRPKNRRVYE PRSLKDIQTI
      51  PEEERTEPVP EGYFGWVEYL LSKPHSFLIQ HTSVDGYFLL RYIGIVGSLS
     101  FVGCLLLLPI LLPVNATNGN NLQGFELLSF SNVTNKNRFY AHVFLSWIFF
     151  GLFTYVIYKE LYYYVVFRHA MQTTPLYDGL LSSRTVIVTE LHKSIAQEGE
     201  MQMRFPKASN VAFAYDLSDL QELCKERAKN AAKYEAALNK VLNKCVKMTR
     251  NKTQKQLDKL YNNGTKPKDD LETYVPHKKR PKHRLGKLPL CLGGKKVNTL
     301  SYSSKRIGEL NEEIHEKQAD WASNDRQPAC FIQFETQLEA QRCYQSVEAI
     351  LGKKNFGKRL IGYSPEDVNW GSMRLSSKER HSRRAVANTI MVLLIIFWAF
     401  PVAVVGIISN VNFLTDKVPF LRFINNMPTF LMGVITGLLP TIALVVLMSL
     451  VPPFIVMLGK LSGCVTRQET DLYSQAWYYA FAVIQIFLVV TATSSASSTV
     501  DSIIDRPRSA MTLLANNLPK ASNFYIMYFI LKGLTGPTWT ILQAVNLLLS
     551  KVLGRVLDST PRQKWNRYNT LATPRMGIVY PGIEILVCIY ICYSIIAPIL
     601  LFFSTVMLTL LYVAYLYNLN YVFGFSFDLK GRNYPRALFQ IFVGIYLSEV
     651  CLLGLFIMAK TWGPLVLEVF WIVVTALAHI YMKRKFIPLF DAVPLSAIRH
     701  ARGEPGYSYP TSDLGLQEIK DIADEMKGKY EQDNTHGILT PVTKDDLKKA
     751  NLIPDNDGSS ENGTPSNPFE SGSERASLSG SNAESDSIKK LNDTVIKKSS
     801  TLSSSTKDNN ESTFVPEGEK FRKFHYSDVE ALRNKRPYDE DDHSKHGPEG
     851  AVPVNADAGV IYSDPAAVMK EPQAFPPDVL ETNTWTRRIL QFFNPRRSYP
     901  FDSVRMRFPL VFNTSIEYDE EYLSSAYTDP CVREKDPIVW CCKDPLGVSK
     951  QQIQEARSNG LDVRDDFTRY DEKGKVIFTY NPPDYEPEAK K*

external links for Phm7p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Candida (CGD) BioPIXIE MIPS YeastGFP
Candida (CandidaDB) CYC2008 (complexes) Pfam domains YeastRC Public Image Repository
YGOB Complexome YeastRC Structure Prediction (Seattle)
YOGY GeneMANIA


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Phm7p
1) Ogawa N, et al.  (2000) New components of a system for phosphate accumulation and polyphosphate metabolism in Saccharomyces cerevisiae revealed by genomic expression analysis. Mol Biol Cell 11(12):4309-21
2) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
3) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76