REX4/YOL080C Protein Information

Standard Name	Rex4p 1
Systematic Name	Yol080cp
ORF Classification	Verified
Description	Putative RNA exonuclease possibly involved in pre-rRNA processing and ribosome assembly (2)
Name Description	Rna EXonuclease 1

Experimental Data
Molecules/cell	4280 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	289
Molecular Weight (Da)	32,895
Isoelectric Point (pI)	10.65

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rex4p (InterPro)
Physical Interactions	There are 9 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00000698FF \| Q08237 MIPS: YOL080C NCBI: 1419913 \| 6324493 \| 74676463 \| NP_014561.1 \| NM_001183334.1 GenBank/EMBL/DDBJ: DAA10704.1 \| Z74822
External Classifications	EC: 3.1.-.- [Hydrolases acting on ester bonds ]

Amino Acid Sequence (or in FASTA format)
1 MALSSNWQAL LASESNPTSN GKNKQSNRKI RNVKKVSKTV NVSSTTQYAP 51 RKRKNGSKIM DMVYNMNKEI SKHEKDKLEG KVFEFNPNKA NTSTTIKEPV 101 KVGISEDTRI NSNKSKEIGK YIAMDCEFVG VGPEGKESAL ARISIVNYFG 151 HVVLDEFVKP REKVVEWRTW VSGIKPEHMK NAITFKEAQK KTADILEGRI 201 LVGHALKHDL EALMLSHPKS LLRDTSRHLP FRKLYAKGKT PSLKKLTREV 251 LKISIQEGEH SSVEDARATM LLYKKEKTEF EKIHRNTFN*

Amino Acid Sequence (or in FASTA format)

       1  MALSSNWQAL LASESNPTSN GKNKQSNRKI RNVKKVSKTV NVSSTTQYAP
      51  RKRKNGSKIM DMVYNMNKEI SKHEKDKLEG KVFEFNPNKA NTSTTIKEPV
     101  KVGISEDTRI NSNKSKEIGK YIAMDCEFVG VGPEGKESAL ARISIVNYFG
     151  HVVLDEFVKP REKVVEWRTW VSGIKPEHMK NAITFKEAQK KTADILEGRI
     201  LVGHALKHDL EALMLSHPKS LLRDTSRHLP FRKLYAKGKT PSLKKLTREV
     251  LKISIQEGEH SSVEDARATM LLYKKEKTEF EKIHRNTFN*

external links for Rex4p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA
	YeastRC Mass Spec (Seattle)

References cited on this page View Complete Literature Guide for Rex4p

1)	van Hoof A, et al. (2000) Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast. EMBO J 19(6):1357-65
2)	Eppens NA, et al. (2002) Deletions in the S1 domain of Rrp5p cause processing at a novel site in ITS1 of yeast pre-rRNA that depends on Rex4p. Nucleic Acids Res 30(19):4222-31
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41