MSE1/YOL033W Protein Information

Standard Name	Mse1p 1
Systematic Name	Yol033wp
ORF Classification	Verified
Description	Mitochondrial glutamyl-tRNA synthetase, predicted to be palmitoylated (1, 2)
Name Description	Mitochondrial aminoacyl-tRNA Synthetase, Glutamate (E) 1
Gene Product	mitochondrial glutamyl-tRNA synthetase 1

Experimental Data
Molecules/cell	2940 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	536
Molecular Weight (Da)	61,603
Isoelectric Point (pI)	9.75

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Mse1p (InterPro)
Physical Interactions	There are 10 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001363D0 \| P48525 MIPS: YOL033W NCBI: 1419825 \| 2507428 \| 625182 \| 6324540 \| NP_014609.1 GenBank/EMBL/DDBJ: DAA10748.1 \| L39015 \| Z74775
External Classifications	EC: 6.1.1.17 [Glutamate--tRNA ligase]

Amino Acid Sequence (or in FASTA format)
1 MIMLRIPTRS YCSPSKLIKG VGLSPLKKSL LSKKIKEDIH PSLPVRTRFA 51 PSPTGFLHLG SLRTALYNYL LARNTNGQFL LRLEDTDQKR LIEGAEENIY 101 EILKWCNINY DETPIKQSER KLIYDKYVKI LLSSGKAYRC FCSKERLNDL 151 RHSAMELKPP SMASYDRCCA HLGEEEIKSK LAQGIPFTVR FKSPERYPTF 201 TDLLHGQINL QPQVNFNDKR YDDLILVKSD KLPTYHLANV VDDHLMGITH 251 VIRGEEWLPS TPKHIALYNA FGWACPKFIH IPLLTTVGDK KLSKRKGDMS 301 ISDLKRQGVL PEALINFCAL FGWSPPRDLA SKKHECFSME ELETIFNLNG 351 LTKGNAKVDD KKLWFFNKHF LQKRILNPST LRELVDDIMP SLESIYNTST 401 ISREKVAKIL LNCGGSLSRI NDFHDEFYYF FEKPKYNDND AVTKFLSKNE 451 SRHIAHLLKK LGQFQEGTDA QEVESMVETM YYENGFSRKV TYQAMRFALA 501 GCHPGAKIAA MIDILGIKES NKRLSEGLQF LQREKK*

Amino Acid Sequence (or in FASTA format)

       1  MIMLRIPTRS YCSPSKLIKG VGLSPLKKSL LSKKIKEDIH PSLPVRTRFA
      51  PSPTGFLHLG SLRTALYNYL LARNTNGQFL LRLEDTDQKR LIEGAEENIY
     101  EILKWCNINY DETPIKQSER KLIYDKYVKI LLSSGKAYRC FCSKERLNDL
     151  RHSAMELKPP SMASYDRCCA HLGEEEIKSK LAQGIPFTVR FKSPERYPTF
     201  TDLLHGQINL QPQVNFNDKR YDDLILVKSD KLPTYHLANV VDDHLMGITH
     251  VIRGEEWLPS TPKHIALYNA FGWACPKFIH IPLLTTVGDK KLSKRKGDMS
     301  ISDLKRQGVL PEALINFCAL FGWSPPRDLA SKKHECFSME ELETIFNLNG
     351  LTKGNAKVDD KKLWFFNKHF LQKRILNPST LRELVDDIMP SLESIYNTST
     401  ISREKVAKIL LNCGGSLSRI NDFHDEFYYF FEKPKYNDND AVTKFLSKNE
     451  SRHIAHLLKK LGQFQEGTDA QEVESMVETM YYENGFSRKV TYQAMRFALA
     501  GCHPGAKIAA MIDILGIKES NKRLSEGLQF LQREKK*

external links for Mse1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Mse1p

1)	Tzagoloff A and Shtanko A (1995) Mitochondrial and cytoplasmic isoleucyl-, glutamyl- and arginyl-tRNA synthetases of yeast are encoded by separate genes. Eur J Biochem 230(2):582-6
2)	Ren J, et al. (2008) CSS-Palm 2.0: an updated software for palmitoylation sites prediction. Protein Eng Des Sel 21(11):639-44
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41