RCL1/YOL010W Protein Information Help

RCL1 BASIC PROTEIN INFORMATION

Standard Name Rcl1p 1
Systematic Name Yol010wp
ORF Classification Verified
Description Subunit of U3-containing 90S preribosome processome complex involved in 18S rRNA biogenesis and small ribosomal subunit assembly; stimulates Bms1p GTPase and U3 binding activity; similar to RNA cyclase-like proteins but no activity detected ( 1, 2, 3 )
Name Description Rna 3'-terminal phosphate Cyclase Like 1
Experimental Data
Molecules/cell 10000 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 367
Molecular Weight (Da) 40,170
Isoelectric Point (pI) 9.41

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Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Rcl1p (InterPro)
Physical Interactions There are 43 total curated physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | PSI-BLAST | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
Secondary Structure Prediction GCG:PepPlot | GCG:PepStruct | GCG:Helical Wheel
External Sequence Databases EBI: Q08096 | UPI000005319E
MIPS: YOL010W
NCBI: NP_014633.1 | 6324564
GenBank/EMBL/DDBJ: CAA99009.1
Amino Acid Sequence (or in FASTA format)
 
       1  MSSSAPKYTT FQGSQNFRLR IVLATLSGKP IKIEKIRSGD LNPGLKDYEV
      51  SFLRLIESVT NGSVIEISYT GTTVIYRPGI IVGGASTHIC PSSKPVGYFV
     101  EPMLYLAPFS KKKFSILFKG ITASHNDAGI EAIKWGLMPV MEKFGVRECA
     151  LHTLKRGSPP LGGGEVHLVV DSLIAQPITM HEIDRPIISS ITGVAYSTRV
     201  SPSLVNRMID GAKKVLKNLQ CEVNITADVW RGENSGKSPG WGITLVAQSK
     251  QKGWSYFAED IGDAGSIPEE LGEKVACQLL EEISKSAAVG RNQLPLAIVY
     301  MVIGKEDIGR LRINKEQIDE RFIILLRDIK KIFNTEVFLK PVDEADNEDM
     351  IATIKGIGFT NTSKKIA*

EXTERNAL LINKS for Rcl1p

Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YGAC Triples
Ashbya (AGD) BOND GPMdb (Mass Spec.)
Candida (CGD) BioPIXIE MIPS
Candida (CandidaDB) CYC2008 (complexes) Pfam domains
YGOB DIP PhosphoPep Database
YOGY YeastRC Two-Hybrid (Seattle) YeastRC Structure Prediction (Seattle)

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for Rcl1p ]

1) Billy E, et al.  (2000) Rcl1p, the yeast protein similar to the RNA 3'-phosphate cyclase, associates with U3 snoRNP and is required for 18S rRNA biogenesis. EMBO J 19(9):2115-26
2) Grandi P, et al.  (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15
3) Karbstein K, et al.  (2005) An essential GTPase promotes assembly of preribosomal RNA processing complexes. Mol Cell 20(4):633-43
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41