DBP6/YNR038W Protein Information

Standard Name	Dbp6p 1
Systematic Name	Ynr038wp
ORF Classification	Verified
Description	Essential protein involved in ribosome biogenesis; putative ATP-dependent RNA helicase of the DEAD-box protein family (1)
Name Description	Dead Box Protein 1

Experimental Data
Molecules/cell	12700 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	629
Molecular Weight (Da)	70,361
Isoelectric Point (pI)	6.19

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Dbp6p (InterPro)
Physical Interactions	There are 12 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000128F2D \| P53734 MIPS: YNR038W NCBI: 1302541 \| 1730678 \| 6324366 \| NP_014436.1 \| NM_001183215.1 GenBank/EMBL/DDBJ: DAA10580.1 \| Z71653
External Classifications	EC: 3.6.1.- [Hydrolases acting on acid anhydrides in phosphorous-containing anhydrides] EC: 3.6.4.13 [RNA helicase]

Amino Acid Sequence (or in FASTA format)
1 MFASRFDPSQ LTAPAASAPE GIVGTTPPAI VPLKRQATES DNEEYGSHQD 51 SDESSNSSSE EDEDRMQVDY GASEEDSSEV EEEESKPSTH STVLSRFKQT 101 VSLQERLGAS DIAESKEDEG IEDEAASTHQ LKQIPQPEFV KNPMNLNTNS 151 LQFKSTGWLN TEKIYYDNSL IKPFSDYANE LEAKLLQNIC KNFSTNTFPI 201 QSIILDSILP VLNFTLNVSK RNFTRRIGDI LVNAATGSGK TLAYSIPIVQ 251 TLFKRQINRL RCIIIVPTKL LINQVYTTLT KLTQGTSLIV SIAKLENSLK 301 DEHKKLSNLE PDILITTPGR LVDHLNMKSI NLKNLKFLII DEADRLLNQS 351 FQGWCPKLMS HLKTDKLDTL PGNVIKMIFS ATLTTNTEKL NGLNLYKPKL 401 FLKQTDKLYQ LPNKLNEFNI NIPTAKSVYK PLILLYSICQ FMAHSPIAAK 451 ILIFVKSNES SIRLSKLLQL ICESRSQSSV LKNLQNLAVS INSVNSNNSK 501 AENKKIVANF SHHSESAGIT ILITTDIMSR GIDINDITQV INYDPPMSSQ 551 QYVHRVGRTA RANELGSAYN LLVGRGERTF FDDLNKDLDR DGKSVQPLEL 601 DFTLLESDSE LYTSSLESLK NYHNNTAQA*

Amino Acid Sequence (or in FASTA format)

       1  MFASRFDPSQ LTAPAASAPE GIVGTTPPAI VPLKRQATES DNEEYGSHQD
      51  SDESSNSSSE EDEDRMQVDY GASEEDSSEV EEEESKPSTH STVLSRFKQT
     101  VSLQERLGAS DIAESKEDEG IEDEAASTHQ LKQIPQPEFV KNPMNLNTNS
     151  LQFKSTGWLN TEKIYYDNSL IKPFSDYANE LEAKLLQNIC KNFSTNTFPI
     201  QSIILDSILP VLNFTLNVSK RNFTRRIGDI LVNAATGSGK TLAYSIPIVQ
     251  TLFKRQINRL RCIIIVPTKL LINQVYTTLT KLTQGTSLIV SIAKLENSLK
     301  DEHKKLSNLE PDILITTPGR LVDHLNMKSI NLKNLKFLII DEADRLLNQS
     351  FQGWCPKLMS HLKTDKLDTL PGNVIKMIFS ATLTTNTEKL NGLNLYKPKL
     401  FLKQTDKLYQ LPNKLNEFNI NIPTAKSVYK PLILLYSICQ FMAHSPIAAK
     451  ILIFVKSNES SIRLSKLLQL ICESRSQSSV LKNLQNLAVS INSVNSNNSK
     501  AENKKIVANF SHHSESAGIT ILITTDIMSR GIDINDITQV INYDPPMSSQ
     551  QYVHRVGRTA RANELGSAYN LLVGRGERTF FDDLNKDLDR DGKSVQPLEL
     601  DFTLLESDSE LYTSSLESLK NYHNNTAQA*

external links for Dbp6p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Dbp6p

1)	Kressler D, et al. (1998) Dbp6p is an essential putative ATP-dependent RNA helicase required for 60S-ribosomal-subunit assembly in Saccharomyces cerevisiae. Mol Cell Biol 18(4):1855-65
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41