NRM1/YNR009W Protein Information

Standard Name	Nrm1p 1
Systematic Name	Ynr009wp
ORF Classification	Verified
Description	Transcriptional co-repressor of MBF (MCB binding factor)-regulated gene expression; Nrm1p associates stably with promoters via MBF to repress transcription upon exit from G1 phase (1)
Name Description	Negative Regulator of MBF targets 1

Experimental Data
Molecules/cell	2880 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	249
Molecular Weight (Da)	27,564
Isoelectric Point (pI)	10.84

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Nrm1p (InterPro)
Physical Interactions	There are 20 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013BAB1 \| P53718 MIPS: YNR009W NCBI: 1302484 \| 1730662 \| 51012695 \| 6324336 \| 836650 \| NP_014406.1 GenBank/EMBL/DDBJ: DAA10550.1 \| AY692622 \| X77395 \| Z71624

Amino Acid Sequence (or in FASTA format)
1 MSIMKQRLPL GEFSSSKINK LAIANIADAS EPRNHGENNV GTVCLPSIKS 51 LMVSPEVYEN TKSLPVPLMR SSGGGMACAS KSSCQDGIST KTTSRDYSEL 101 SKKLQIRLQF AYYKYKTKQT DKNFTDLKSK HSITRPSKVA THSKSEPLTR 151 RRKLVLSQGH YKTPARSKIK TPSSICSHDN TSSFTSFRGV SESSSTTADM 201 NVADTTTPIR NNINTKHSNS HNRTLYQRQE TPTSIKAAKS LIHLFTSNQ*

Amino Acid Sequence (or in FASTA format)

       1  MSIMKQRLPL GEFSSSKINK LAIANIADAS EPRNHGENNV GTVCLPSIKS
      51  LMVSPEVYEN TKSLPVPLMR SSGGGMACAS KSSCQDGIST KTTSRDYSEL
     101  SKKLQIRLQF AYYKYKTKQT DKNFTDLKSK HSITRPSKVA THSKSEPLTR
     151  RRKLVLSQGH YKTPARSKIK TPSSICSHDN TSSFTSFRGV SESSSTTADM
     201  NVADTTTPIR NNINTKHSNS HNRTLYQRQE TPTSIKAAKS LIHLFTSNQ*

external links for Nrm1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS	YeastRC Public Image Repository
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Nrm1p

1)	de Bruin RA, et al. (2006) Constraining G1-specific transcription to late G1 phase: the MBF-associated corepressor Nrm1 acts via negative feedback. Mol Cell 23(4):483-96
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41