PEX6/YNL329C Protein Information Help

Standard Name Pex6p 1
Systematic Name Ynl329cp
Alias Pas8p 2
ORF Classification Verified
Description AAA-peroxin that heterodimerizes with AAA-peroxin Pex1p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol (2, 3, 4)
Name Description PEroXin 1
Experimental Data
Molecules/cell 1630 5
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 1,030
Molecular Weight (Da) 115,570
Isoelectric Point (pI) 5.44

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Pex6p (InterPro)
Physical Interactions There are 37 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00001316F1 | P33760
MIPS: YNL329C
NCBI: 1302449 | 393287 | 464348 | 6324000 | 633657 | 642339 | NP_014070.1
GenBank/EMBL/DDBJ: DAA10234.1 | L20789 | X83226 | Z46259 | Z71605
Amino Acid Sequence (or in FASTA format)
 
       1  MKASLTFSLS GIYAPCSISR DIYLEYGDKK AECLYGTIRL PQYGPGCTPG
      51  KIVHCVLDDS LPFCSIVVPS KLFGFMPTQP TMDFCYFEPI LDNVVPVLDS
     101  VTFLINEQLY SKLMDLPQEM QQIQFLHYKY NINSMETVVH SRDILTSGLC
     151  QILNCSPFPQ GLVDFTETQL ILVNDTEQKL SALKYANEDE EYALPKIGTN
     201  SALSIDLESL PCTISRDLLR PAPHINDDNS IYAFTDAETL LRLDVTSGSF
     251  ITVSNMGCVR LVKLFVLLLP NGFKKRTIYA PPKIIASFPD CSVVTISKSN
     301  IGHTDIPIAN QVFISRVGGW LQSQKCFQNI ILTTLKKFFS ESKRILCQND
     351  LIPIAFDSSM ADLNIAEEND ESDDEDELGQ YYKNDSLVWF FVTSAELDCF
     401  SKDNSHFIID PNRTKLITTN ITNRRPLPLS RSNLQRYYGF AETFYYDLHI
     451  FPYVRQLVNI LETSFNCSQR GITLNASVLL HSTTNNVGKA TMVRFASKYL
     501  GIHLLEIDCL SLTSNSRQLD STSKIIGYIR AKCENVLPYA SPAVIFLAHL
     551  DSILLDVNAN QDPEAIKLQK SINFEMSKLL DDFTFKFPGT TFVGSVNNID
     601  NVPSSFRSHM RFEILVPVPS EAQRLRIFQW YLSSHELNRD VQQKVPVSYM
     651  DNISFSSLSS YSAGLTPLDI KSIVETARMT ATARFYQESK KCGWLPQSIL
     701  ITQEDLSKAT SKARNEFSVS IGAPQIPNVT WDDIGGIDFV KGEILDTIDM
     751  PLKHPELFTS GMKKRSGILF YGPPGTGKTL MAKAIATNFS LNFFSVKGPE
     801  LLNMYIGESE ANVRRVFQKA REAKPCVIFF DEIDSVAPKR GNQGDSGGVM
     851  DRIVSQLLAE LDGMSTDADG VFVIGATNRP DLLDEALLRP GRFDKLLYLG
     901  IPDTDTKQLN ILEALTRKFV LDNDVKLIEL AKLCPFNYTG ADFYALCSDA
     951  MLNAMSRIAR MVEKKVSQHN ELTGENISTR RWFDKIATKE DTKVVVKMED
    1001  FLKAQEQLTP SVSRAELNHY EAVRANFEGA *

external links for Pex6p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Aspergillus (AspGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CGD) CYC2008 (complexes) Pfam domains
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Pex6p
1) Distel B, et al.  (1996) A unified nomenclature for peroxisome biogenesis factors. J Cell Biol 135(1):1-3
2) Voorn-Brouwer T, et al.  (1993) Sequence of the PAS8 gene, the product of which is essential for biogenesis of peroxisomes in Saccharomyces cerevisiae. Biochim Biophys Acta 1216(2):325-8
3) Birschmann I, et al.  (2005) Structural and functional analysis of the interaction of the AAA-peroxins Pex1p and Pex6p. FEBS J 272(1):47-58
4) Platta HW, et al.  (2005) Functional role of the AAA peroxins in dislocation of the cycling PTS1 receptor back to the cytosol. Nat Cell Biol 7(8):817-22
5) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41