PHA2/YNL316C Protein Information

Standard Name	Pha2p
Systematic Name	Ynl316cp
ORF Classification	Verified
Description	Prephenate dehydratase, catalyzes the conversion of prephanate to phenylpyruvate, which is a step in the phenylalanine biosynthesis pathway (1)
Name Description	PHenylAlanine requiring

Experimental Data
Molecules/cell	2020 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	334
Molecular Weight (Da)	38,225
Isoelectric Point (pI)	6.14

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Pha2p (InterPro)
Physical Interactions	There are 5 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001D479F \| P32452 MIPS: YNL316C NCBI: 116242709 \| 1172472 \| 1302425 \| 171120 \| 37362685 \| 633667 \| NP_014083.2 GenBank/EMBL/DDBJ: DAA10245.1 \| M87006 \| Z46259 \| Z71592
External Classifications	EC: 4.2.1.51 [Prephenate dehydratase]

Amino Acid Sequence (or in FASTA format)
1 MASKTLRVLF LGPKGTYSHQ AALQQFQSTS DVEYLPAASI PQCFNQLEND 51 TSIDYSVVPL ENSTNGQVVF SYDLLRDRMI KKALSLPAPA DTNRITPDIE 101 VIAEQYVPIT HCLISPIQLP NGIASLGNFE EVIIHSHPQV WGQVECYLRS 151 MAEKFPQVTF IRLDCSSTSE SVNQCIRSST ADCDNILHLA IASETAAQLH 201 KAYIIEHSIN DKLGNTTRFL VLKRRENAGD NEVEDTGLLR VNLLTFTTRQ 251 DDPGSLVDVL NILKIHSLNM CSINSRPFHL DEHDRNWRYL FFIEYYTEKN 301 TPKNKEKFYE DISDKSKQWC LWGTFPRNER YYHK*

Amino Acid Sequence (or in FASTA format)

       1  MASKTLRVLF LGPKGTYSHQ AALQQFQSTS DVEYLPAASI PQCFNQLEND
      51  TSIDYSVVPL ENSTNGQVVF SYDLLRDRMI KKALSLPAPA DTNRITPDIE
     101  VIAEQYVPIT HCLISPIQLP NGIASLGNFE EVIIHSHPQV WGQVECYLRS
     151  MAEKFPQVTF IRLDCSSTSE SVNQCIRSST ADCDNILHLA IASETAAQLH
     201  KAYIIEHSIN DKLGNTTRFL VLKRRENAGD NEVEDTGLLR VNLLTFTTRQ
     251  DDPGSLVDVL NILKIHSLNM CSINSRPFHL DEHDRNWRYL FFIEYYTEKN
     301  TPKNKEKFYE DISDKSKQWC LWGTFPRNER YYHK*

external links for Pha2p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Pha2p

1)	Maftahi M, et al. (1995) Sequencing analysis of a 24.7 kb fragment of yeast chromosome XIV identifies six known genes, a new member of the hexose transporter family and ten new open reading frames. Yeast 11(11):1077-85
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41