YPT11/YNL304W Protein Information

Standard Name	Ypt11p 1
Systematic Name	Ynl304wp
ORF Classification	Verified
Description	Rab family GTPase that interacts with the C-terminal tail domain of Myo2p; mediates distribution of mitochondria and endoplasmic reticuli to daughter cells (1, 2, 3, 4)
Name Description	Yeast Protein Two 1

Experimental Data
Molecules/cell	2850 5

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	417
Molecular Weight (Da)	47,116
Isoelectric Point (pI)	6.78

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ypt11p (InterPro)
Physical Interactions	There are 21 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000603763 \| P48559 MIPS: YNL304W NCBI: 1050856 \| 1302400 \| 1353102 \| 239938804 \| 82795261 \| NP_014095.2 GenBank/EMBL/DDBJ: DAA10257.1 \| U23084 \| Z71580

Amino Acid Sequence (or in FASTA format)
1 MSQRKRYSLN VVTSPSIPSP TPSAPIRTNE SNWEAASPAS AASSFLPNVH 51 HGGTVLNPGL GIMRSPSLNK SGAFGRSGSS GSSTVIEPSN IKLLLIGDAN 101 VGKTAMILSY CRELLTRAEM SRSARLRHQQ QQQHKDLGLK KTVVNHRLSM 151 KEKRKRYSSN DFEKEFKDIN HFADETSDFG NPNIGDDNNH EMADPNEIVI 201 ETRSTIGIDI KTNLVNIDNR FFNVILWDTA GQERYQNAII PSLYKKTNAV 251 ILTYDITNAK SFQSCMERWI VQALENFSSQ DLLKARFFLV GNKIDLYKER 301 QVTHYDVVQM VQEMQLKHGI KISGNFEVSC KWVNVVERTM NMIILDLVEN 351 GCFENNDPCV SITTSDDVQG HEQEFHDTVE EPFNFTRQRQ HQLEKNNTVD 401 ITKPNDDIAN NQSICCV*

Amino Acid Sequence (or in FASTA format)

       1  MSQRKRYSLN VVTSPSIPSP TPSAPIRTNE SNWEAASPAS AASSFLPNVH
      51  HGGTVLNPGL GIMRSPSLNK SGAFGRSGSS GSSTVIEPSN IKLLLIGDAN
     101  VGKTAMILSY CRELLTRAEM SRSARLRHQQ QQQHKDLGLK KTVVNHRLSM
     151  KEKRKRYSSN DFEKEFKDIN HFADETSDFG NPNIGDDNNH EMADPNEIVI
     201  ETRSTIGIDI KTNLVNIDNR FFNVILWDTA GQERYQNAII PSLYKKTNAV
     251  ILTYDITNAK SFQSCMERWI VQALENFSSQ DLLKARFFLV GNKIDLYKER
     301  QVTHYDVVQM VQEMQLKHGI KISGNFEVSC KWVNVVERTM NMIILDLVEN
     351  GCFENNDPCV SITTSDDVQG HEQEFHDTVE EPFNFTRQRQ HQLEKNNTVD
     401  ITKPNDDIAN NQSICCV*

external links for Ypt11p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
YGOB	BioPIXIE	MIPS	YeastGFP
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Ypt11p

1)	Lazar T, et al. (1997) Vesicular transport: how many Ypt/Rab-GTPases make a eukaryotic cell? Trends Biochem Sci 22(12):468-72
2)	Itoh T, et al. (2002) Complex formation with Ypt11p, a rab-type small GTPase, is essential to facilitate the function of Myo2p, a class V myosin, in mitochondrial distribution in Saccharomyces cerevisiae. Mol Cell Biol 22(22):7744-57
3)	Itoh T, et al. (2004) Mmr1p is a mitochondrial factor for Myo2p-dependent inheritance of mitochondria in the budding yeast. EMBO J 23(13):2520-30
4)	Buvelot Frei S, et al. (2006) Bioinformatic and comparative localization of Rab proteins reveals functional insights into the uncharacterized GTPases Ypt10p and Ypt11p. Mol Cell Biol 26(19):7299-317
5)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41