SEC21/YNL287W Protein Information Help

Standard Name Sec21p 1
Systematic Name Ynl287wp
ORF Classification Verified
Description Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p forms the COPI coat; involved in ER to Golgi transport of selective cargo (2, 3)
Name Description SECretory
Experimental Data
Molecules/cell 77900 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 935
Molecular Weight (Da) 104,830
Isoelectric Point (pI) 4.84

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Sec21p (InterPro)
Physical Interactions There are 95 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000053028 | P32074
MIPS: YNL287W
NCBI: 1302369 | 1706001 | 171483 | 6324042 | NP_014112.1
GenBank/EMBL/DDBJ: DAA10272.1 | M59708 | Z71563
Amino Acid Sequence (or in FASTA format)
 
       1  MSAHTYKKFE NSTSGDLPDK MTIYQDCMNT FNESPVNSKR CRLLISRLLR
      51  LLAQGETFPQ NEATALFFSI SKLFQHQNDP LRQAVYLAIK ELSGISEDVL
     101  MATSSIMKDV QNGSDLIKPD AIRSLTYVLD ESTAFSAERL LKSAVVSRHP
     151  SISSAALCTS YHLLPISEVT IRRFTNETQE AVLDLKQFPN QHGNSEYYPN
     201  STYISQYHAL GLLYQLKKTD KMALLKLVRH FSENNSMKNQ LAKVELVKIV
     251  NDLIYRDPQL FSQFRPLLSD WLSNKFESVQ LETAKLITSF ATRNSRLVAP
     301  ELYAAAISAL QSLLTVPRVS SRFAALRILN RISMVSPEKI VVCNPELESL
     351  INDSNRNIST YAITTLLKTG TSKNISSLIS TITNFIHDVS DDFKIIIIDA
     401  VRTLSLNFPQ EWKSILNFLI DVLKNSEGGF KFKNSIVEAL IDIVSFVPQS
     451  KELALENLCD FIEDCEFNEI LVRILHLLGK EGPSAPNPSL YVRHIYNRVV
     501  LENSIIRSAA VVALSKFALT KNDPTLYESI ISLLKRIAND KDDEVRDRAT
     551  IALEFIDSAR NKDDVIAQNL IESKYFYDIP SLESKLSSYI SSNTDSFATA
     601  FDVNQVRKFT EDEMKAINLK RKQEQIFNQK SETTLDTTPE AESVPEKRAD
     651  ANSFAGPNLD DHQEDLLATK YADELLSIEQ IKPFGQLVNS SRAISLTEPE
     701  AEFVVRGVKH LFKDNVVLQF NITNTLTDIA LDNVSVVCTP EISDEAELEE
     751  LFTLQVDRLL PSEEAACYVA FKKLDEIVME GFLNNLTFTT KEINPDTNEP
     801  FDGDEGFQDE YEIDSIFLNA GDYVKSSFTG NFSATFDELP CEEVAVFNIQ
     851  EDLSIQEVVD KIILNSSCLP VESTQFAPSD SNSHTLKLFG KSALTGSKVA
     901  LQIKMIKSSK GLALKVHGKG EDSLLCSDLV NGLMQ*

external links for Sec21p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Candida (CGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CandidaDB) CYC2008 (complexes) Pfam domains
YGOB Complexome YeastRC Structure Prediction (Seattle)
YOGY DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Sec21p
1) Novick P, et al.  (1980) Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell 21(1):205-15
2) Gaynor EC and Emr SD  (1997) COPI-independent anterograde transport: cargo-selective ER to Golgi protein transport in yeast COPI mutants. J Cell Biol 136(4):789-802
3) Spang A, et al.  (2001) The ADP ribosylation factor-nucleotide exchange factors Gea1p and Gea2p have overlapping, but not redundant functions in retrograde transport from the Golgi to the endoplasmic reticulum. Mol Biol Cell 12(4):1035-45
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41