ATX1/YNL259C Protein Information 
| Standard Name | Atx1p |
|---|---|
| Systematic Name | Ynl259cp |
| ORF Classification | Verified |
| Description | Cytosolic copper metallochaperone that transports copper to the secretory vesicle copper transporter Ccc2p for eventual insertion into Fet3p, which is a multicopper oxidase required for high-affinity iron uptake (1, 2) |
| Name Description | AnTioXidant 1 |
| Click on image for expanded interactive view |
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| Post-translational Modifications | PhosphoGRID | PhosphoPep Database |
|---|---|
| Domains/motifs | See the graphical view and list of proteins that share domains/motifs in common with Atx1p (InterPro) |
| Physical Interactions | There are 9 total physical interactions (BioGRID) |
| Homologs | PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer |
| External Sequence Databases |
EBI: UPI0000110BE0 | P38636 MIPS: YNL259C NCBI: 114794062 | 1255959 | 1302311 | 13787052 | 253722842 | 269914563 | 269914564 | 269914565 | 269914566 | 269914567 | 269914568 | 269914569 | 269914570 | 269914571 | 269914572 | 269914573 | 269914574 | 45270624 | 530996 | 584821 | 6324070 | 6730163 | 6730164 | NP_014140.1 GenBank/EMBL/DDBJ: DAA10300.1 | AY558367 | L35270 | X96722 | Z71535 |
external links for Atx1p
| Homologs | Interaction Resources | Protein databases/Other | Localization Resources |
|---|---|---|---|
| BLASTP (NCBI) | BioGRID | SCOP Superfamily | Organelle DB |
| Ashbya (AGD) | BOND | GPMdb (Mass Spec.) | YPL+ |
| Aspergillus (AspGD) | BioPIXIE | MIPS | YeastGFP |
| Candida (CGD) | CYC2008 (complexes) | Pfam domains | YeastRC Public Image Repository |
| Candida (CandidaDB) | Complexome | YeastRC Structure Prediction (Seattle) | |
| YGOB | DIP | ||
| YOGY | GeneMANIA |
References cited on this page View Complete Literature Guide for Atx1p
| 1) | Lin SJ and Culotta VC (1995) The ATX1 gene of Saccharomyces cerevisiae encodes a small metal homeostasis factor that protects cells against reactive oxygen toxicity. Proc Natl Acad Sci U S A 92(9):3784-8 |
| 2) | Lin SJ, et al. (1997) A role for the Saccharomyces cerevisiae ATX1 gene in copper trafficking and iron transport. J Biol Chem 272(14):9215-20 |
